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Naunyn-Schmiedeberg's Archives of Pharmacology · 2025 · Vol. 398 · Issue 7 · Springer
Non-small cell lung cancer (NSCLC) is a widespread highly malignant type of lung cancer. Conventional chemotherapeutic drugs may be accompanied by both drug resistance and serious side effects in patients. Therefore, safer and more effective medications are urgently needed for the treatment of NSCLC. This study investigates the mode of action of 21 phytoconstituents previously isolated from the Amaryllidaceous plants Crinum bu...
Journal of Applied Phycology · 2025 · Vol. 37 · Issue 3 · Springer
Previous studies have focused on long-term dietary supplementation of fish with the diatom Amphora coffeaeformis to prevent infections. This study introduces a novel approach by assessing short-term post-infection administration of A. coffeaeformis to mitigate Aeromonas sobria infection in Nile tilapia ( Oreochromis niloticus ). This approach addresses the need for sustainable strategies to manage infections after onset, reduc...
Journal of Applied Phycology · 2025 · Vol. 37 · Issue 2 · Springer
Climate change affects aquaculture to a significant extent, while one of the primary threats to Nile tilapia ( Oreochromis niloticus ) growth and health is suboptimal temperatures. The objective of this study was to assess the effects of Amphora coffeaeformis powder and extract on the growth performance and health status of tilapia grown in suboptimal temperature (21 °C). A total of 180 fish (31.39 ± 0.5 g) were randomly alloc...
Naunyn-Schmiedeberg's Archives of Pharmacology · 2024 · Vol. 397 · Issue 10 · Springer
Nicotine, a pervasive global environmental pollutant, is released throughout every phase of the tobacco’s life cycle. This study examined the probable ameliorative role of Chlorella vulgaris (ChV) extract against nicotine (NIC)-induced hepatic injury in Ehrlich ascites carcinoma (EAC) bearing female Swiss mice. Sixty female Swiss mice were assigned to four equal groups orally gavaged 2% saccharin 0.2 mL/mouse (control group),...
DARU Journal of Pharmaceutical Sciences · 2023 · Vol. 31 · Issue 1 · Springer
Background Adiposity and non-alcoholic fatty liver disease (NAFLD) are common characteristics of metabolic syndrome (MS). Understanding the underlying pathogenesis is crucial for the development of new remedies. Resveratrol controls obesity and glycemic disorders in patients with MS. Objectives This study aimed to evaluate the effect of resveratrol and dulaglutide on adipose tissues and liver in rats with MS, declaring their p...