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Assessing the palatability of different meats consumed in a biodiversity hotspot to inform alternative protein interventionsNARA Subscribed
Alternative protein interventions are common in conservation. They aim to reduce the hunting or consumption of wildlife by promoting substitutes. However, selecting suitable meat substitutes is challenging because many factors drive wild meat consumption. Palatability, one such factor, drives consumer food preference and is potentially crucial in determining meat substitutability in the context of alternative protein intervent...
Background To date, azoles represent the only viable option for oral treatment of invasive Candida infections, while rates of azole resistance among non-albicans Candida spp. continue to increase. The objective of this sub-analysis of the European multicenter observational cohort study Candida III was to describe demographical and clinical characteristics of the cohort requiring prolonged hospitalization solely to complete int...
Towards engineering a hybrid carboxysomeNARA Subscribed
Carboxysomes are bacterial microcompartments, whose structural features enable the encapsulated Rubisco holoenzyme to operate in a high-CO 2 environment. Consequently, Rubiscos housed within these compartments possess higher catalytic turnover rates relative to their plant counterparts. This particular enzymatic property has made the carboxysome, along with associated transporters, an attractive prospect to incorporate into pl...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Translation initiation from sequence variants of the bacteriophage T7 g10RBS in Escherichia coli and Agrobacterium fabrumNARA Subscribed
Background The bacteriophage T7 gene 10 ribosome binding site (g10RBS) has long been used for robust expression of recombinant proteins in Escherichia coli . This RBS consists of a Shine–Dalgarno (SD) sequence augmented by an upstream translational “enhancer” (Enh) element, supporting protein production at many times the level seen with simple synthetic SD-containing sequences. The objective of this study was to dissect the g1...
Understanding of the extent of acclimation of light‐saturated net photosynthesis ( A n ) to temperature ( T ), and associated underlying mechanisms, remains limited. This is a key knowledge gap given the importance of thermal acclimation for plant functioning, both under current and future higher temperatures, limiting the accuracy and realism of Earth system model ( ESM ) predictions. Given this, we analysed and modelled T ‐d...
Development of passive sampling devices for bioavailable contaminants of current and emerging concern: Waitemata Harbour case studyNARA Subscribed
Bioavailable contaminant concentrations are an important component in assessing environmental effects as they directly affect ecosystem health. Shellfish contaminant monitoring programmes have traditionally filled this requirement but are being phased out in some jurisdictions. Passive sampling devices (PSDs) have the potential to replace shellfish monitoring; however, there are still knowledge gaps to address before this can...