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Beyond rhodoliths: Community‐level carbon metabolism and calcification in coralline algal bedsNARA Subscribed
Coastal ecosystems play a major role in global carbon cycling and storage, yet the contribution of calcifying macroalgal habitats, such as coralline algal beds (CABs; rhodolith and maerl beds), remains poorly understood. Because carbon cycling in CABs is governed by community productivity and calcification, which exert opposing effects on seawater carbonate chemistry, understanding the balance between these processes is essent...
Fungal Panzootic Increasingly Threatens Temperate Amphibian Species While Impact Has Stabilised in Equatorial RegionsNARA Subscribed
Global amphibian declines outpace the loss of most organisms on Earth. The panzootic fungal disease chytridiomycosis, caused by Batrachochytrium dendrobatidis ( Bd ), is widely regarded as a predominant driver behind amphibian biodiversity erosion. However, a comprehensive global‐scale analysis of the relationship between Bd and extinction risk remains lacking. Using a global database of Bd ‐detections and IUCN Red List extinc...
Combined resistance mechanisms leading to high-level of cefiderocol resistance among NDM-like producing E. coli ST167 clinical isolatesNARA Subscribed
Summary Purpose A series of NDM-producing Escherichia coli ST167 clinical isolates exhibiting resistance to cefiderocol (FDC), with no previous exposure to this antibiotic, were analyzed in this study. Methods The antimicrobial susceptibility testing and phenotypic detection of resistance patterns (Rapid Cefiderocol NP test and MIC determination) were performed for all tested isolates. Their entire genomes were sequenced by us...
Aim The urgency for remote, reliable and scalable biodiversity monitoring amidst mounting human pressures on ecosystems has sparked worldwide interest in Passive Acoustic Monitoring (PAM), which can track life underwater and on land. However, we lack a unified methodology to report this sampling effort and a comprehensive overview of PAM coverage to gauge its potential as a global research and monitoring tool. To address this...
The missing link: ARID1B non-truncating variants causing Coffin-Siris syndrome due to protein aggregationNARA Subscribed
ARID1B is the most frequently mutated gene in Coffin-Siris syndrome (CSS). To date, the vast majority of causative variants reported in ARID1B are truncating, leading to nonsense-mediated mRNA decay. In the absence of experimental data, only few ARID1B amino acid substitutions have been classified as pathogenic, mainly based on clinical data and their de novo occurrence, while most others are currently interpreted as variants...
Chung-Jansen syndrome is a neurodevelopmental disorder characterized by intellectual disability, behavioral problems, obesity and dysmorphic features. It is caused by pathogenic variants in the PHIP gene that encodes for the Pleckstrin homology domain-interacting protein, which is part of an epigenetic modifier protein complex. Therefore, we hypothesized that PHIP haploinsufficiency may impact genome-wide DNA methylation (DNAm...
Effects of human footprint and biophysical factors on the body‐size structure of fished marine speciesNARA Subscribed
Marine fisheries in coastal ecosystems in many areas of the world have historically removed large‐bodied individuals, potentially impairing ecosystem functioning and the long‐term sustainability of fish populations. Reporting on size‐based indicators that link to food‐web structure can contribute to ecosystem‐based management, but the application of these indicators over large (cross‐ecosystem) geographical scales has been lim...
Phenotypic plasticity masks range‐wide genetic differentiation for vegetative but not reproductive traits in a short‐lived plantNARA Subscribed
Genetic differentiation and phenotypic plasticity jointly shape intraspecific trait variation, but their roles differ among traits. In short‐lived plants, reproductive traits may be more genetically determined due to their impact on fitness, whereas vegetative traits may show higher plasticity to buffer short‐term perturbations. Combining a multi‐treatment greenhouse experiment with observational field data throughout the rang...
Marine reserves are a key tool for the conservation of marine biodiversity, yet only ~2.5% of the world's oceans are protected. The integration of marine reserves into connected networks representing all habitats has been encouraged by international agreements, yet the benefits of this design has not been tested empirically. Australia has one of the largest systems of marine reserves, providing a rare opportunity to assess how...