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Rationale Affective behavioral effects of kappa-opioid receptor (KOR) stimulation have been found to vary between the rostral and caudal nucleus accumbens (NAc) shell, but this has so far only been demonstrated in males. Objectives To examine the effects of KOR activation in subregions of the NAc shell on affective and motivated behavior in females. Methods In one group of Long-Evans rats, females were given access to 20% etha...
Five-year psychological impact and surveillance compliance in the Australian Pancreatic Cancer Screening ProgramNARA Subscribed
Evidence of benefit for pancreatic ductal adenocarcinoma (PDAC) surveillance is accumulating, including earlier staging, extended survival, and improved psychological function. This study aimed to assess the 5-year psychological impact of high-risk PDAC surveillance, performed at St Vincent’s Hospital, Sydney, Australia. Participants were offered annual endoscopic ultrasound (EUS) or magnetic resonance imaging (MRI), with freq...
The Case of the Missing Marbles: Forensics for GeoheritageNARA Subscribed
Efficacy of Inhalable Endolysin Cpl-1 Formulations in Combination with Gentamicin or Endolysin Pal in a Murine Lung Infection ModelNARA Subscribed
Purpose Inhalable liquid formulation of endolysins represents a promising alternative to conventional antibiotics. Dry powder formulations offer improved stability for endolysin pulmonary delivery. This study aimed to evaluate the efficacy of an inhalable dry powder or liquid formulation of endolysin Cpl-1 alone and to compare it with liquid combinations of Cpl-1 with either gentamicin or endolysin Pal in a murine model of S....
Quantifying coral reef carbonate budgets: a comparison between ReefBudget and CoralNetNARA Subscribed
Calcium carbonate production constitutes one of the core processes that drive coral reef ecosystem functioning and can be assessed using in-water or image-based survey methods, which have not previously been compared. This study compares carbonate production estimates from in-water ReefBudget surveys and image-based CoralNet analyses in Puerto Rico, Indonesia, and Chagos Archipelago. Methods were compared for different regions...
Morphological and Chemical Changes in the Trophozoites and Cysts of Acanthamoeba Castellanii Induced by Camellia Sinensis ExtractsNARA Subscribed
Purpose Acanthamoeba castellanii is an important opportunistic human protozoal pathogen that can cause both skin, ocular and brain infections. Recent studies have established that brews and solvent extract (SE) of green tea ( Camellia sinensis ) can inhibit the growth and encystation of A. castellanii . Here we characterized those growth and encystation inhibitions. Methods Herein, we characterize of the morphological and chem...
The interconnecting links between individuals in an animal social network are often defined by discrete, directed behaviours, but where these are difficult to observe, a network link (edge) may instead be defined by individuals sharing a space at the same time, which can then be used to infer a social association. The method by which these associations are defined should be informed by the biological significance of edges, and...
Uncovering the magnitude of African pangolin poaching with extensive nanopore DNA genotyping of seized scalesNARA Subscribed
Trade in pangolins is illegal, and yet tons of their scales and products are seized at various ports. These large seizures are challenging to process and comprehensively genotype for upstream provenance tracing and species identification for prosecution. We implemented a scalable DNA barcoding pipeline in which rapid DNA extraction and MinION sequencing were used to genotype a substantial proportion of pangolin scales subsampl...