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Understanding how genetic variants influence disease risk through molecular mechanisms remains a central challenge in complex disease genetics. Nonsyndromic orofacial clefts (OFCs) exemplify this challenge, with most risk loci residing in non-coding regions. We hypothesized that common genetic variants influence OFC risk by modulating DNA methylation at regulatory elements through methylation quantitative trait loci (meQTLs)....
The pygmy ( Kogia breviceps ) and dwarf ( Kogia sima ) sperm whales are cryptic cetaceans characterized by inconspicuous surfacing behavior, small group sizes, and deep‐diving habits, making visual detection particularly challenging. Here, we present the first broad‐scale passive acoustic monitoring (PAM) assessment of Kogia spp. occurrence along the Brazilian coast, spanning both the Equatorial Atlantic Ocean (EAO) and Southw...
Intestinal Histomorphometric Alterations During Experimental Strongyloidiasis in Mice Treated with Rosmarinus officinalis Essential OilNARA Subscribed
Purpose Strongyloidiasis is an intestinal helminthiasis that can induce structural alterations in the intestinal mucosa during infection. The present study evaluated histomorphometric alterations of the small intestine in mice experimentally infected with Strongyloides venezuelensis and treated with Rosmarinus officinalis essential oil. Methods Infected animals were treated orally with R. officinalis essential oil (200 or 400...
Aim We evaluated how native vegetation cover influences the diversity of arachnid assemblages across multiple spatial scales in major Brazilian ecosystems. Location Brazil (Amazon and Atlantic rainforests, Cerrado savanna and Caatinga dry forest). Taxon Arachnida (Opiliones, Pseudoscorpiones and Scorpiones). Methods We sampled arachnids at 120 sites using active search and litter sifting. Native vegetation cover was quantified...
Pyrrhulina australis Eigenmann & Kennedy, 1903, is widely distributed across the main hydrographic basins of South America. The taxonomic integrity of this species is nevertheless challenged by the lack of clear diagnostic characters, its marked geographic variation and the morphological overlap with its congeners. In this context, the present study investigated the genetic diversity of the P. australis group ( P. australis ,...
Seasonality and habitat affect tick parasitism in typical antbirds (Thamnophilidae) of the Atlantic ForestNARA Subscribed
Records of tick parasitism in Brazilian birds result from specific community studies, in which similar parasitic rates are found among species phylogenetically close and with similar habitat use. However, to understand the tick–bird dynamics, it is necessary to consider the ecological aspects of the organisms and the environment. Over a year, during both dry and rainy periods, we captured three Thamnophilidae species with mist...
Coxiella burnetii in ruminants from SomaliaNARA Subscribed
Q fever in humans and coxiellosis in ruminants are caused by Coxiella burnetii , a zoonotic obligate intracellular bacterium. This infection poses significant health and economic risk. Effective control strategies rely on a thorough understanding of their epidemiology. In this study, we examined the prevalence of C. burnetii in 372 ruminants (190 goats, 133 cattle, and 49 sheep) from the Lower Shabelle and Benadir Regions of S...