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Endocannabinoid response to social stress in chronic non-medical prescription opioid usersNARA Subscribed
Rationale The ongoing global opioid crisis underscores the need to better understand the neurobiological mechanisms underlying opioid use disorder (OUD). Stress is a key risk factor for developing and maintaining OUD. While animal models report that the endocannabinoid system (ECS) plays a modulatory role in stress response, alterations of ECS stress reactivity in individuals with OUD have yet to be studied. Objectives Here, w...
Characterizing canopy light penetration in black walnut (Juglans nigra) cultivars to inform selection for alley croppingNARA Subscribed
Eastern black walnut ( Juglans nigra L.) is a nut-producing tree species that breaks dormancy late in the spring, allowing a winter alley crop to ripen before substantial canopy shade is formed. However, there is a high level of variation in the timing and structure of tree canopy development within the black walnut cultivar collection maintained at the University of Missouri Center for Agroforestry (UMCA). To identify cultiva...
Associations of alternative cannabis product use and poly-use with subsequent illicit drug use initiation during adolescenceNARA Subscribed
Rationale Specific cannabis products may differentially increase risk of initiating non-cannabis illicit drug use during adolescence. Objective To determine whether ever- and poly-use of smoked, vaporized, edible, concentrate, or blunt cannabis products are associated with subsequent initiation of non-cannabis illicit drug use. Methods High school students from Los Angeles completed in-classroom surveys. The analytic sample (...
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
Climate variability in marine environments, particularly sea surface temperature (SST), is influenced by natural fluctuations occurring at various temporal and spatial scales. Distinguishing between anthropogenic climate change trends and natural variability is crucial for understanding the complex dynamics of ocean temperatures. This study applies the concept of Time of Emergence (ToE) to estimate when the signal of long-term...
Aquaculture provides an important and expanding source of protein rich and healthy food to the world. However, to minimize environmental harm from aquaculture, interactions with wild fish communities need to be thoroughly assessed. Here, we characterize the existing knowledge pertaining to such interactions, exemplified with Atlantic salmon ( Salmo salar ) farming in open net pens along the Norwegian coast and potential conseq...
Practical Guide to Measuring Wetland Carbon Pools and FluxesNARA Subscribed
Wetlands cover a small portion of the world, but have disproportionate influence on global carbon (C) sequestration, carbon dioxide and methane emissions, and aquatic C fluxes. However, the underlying biogeochemical processes that affect wetland C pools and fluxes are complex and dynamic, making measurements of wetland C challenging. Over decades of research, many observational, experimental, and analytical approaches have bee...
Digital biomarkers and sex impacts in Alzheimer’s disease management — potential utility for innovative 3P medicine approachNARA Subscribed
Digital biomarkers are defined as objective, quantifiable physiological and behavioral data that are collected and measured by means of digital devices. Their use has revolutionized clinical research by enabling high-frequency, longitudinal, and sensitive measurements. In the field of neurodegenerative diseases, an example of a digital biomarker-based technology is instrumental activities of daily living (iADL) digital medical...
Non-Linear Device Head Coupling and Temporal Delays in Large Animal Acceleration Models of Traumatic Brain InjuryNARA Subscribed
Accurate characterization of head kinematics following an external blow represents a fundamental aspect of traumatic brain injury (TBI) research. The majority of previous large animal studies have assumed an equivalent relationship between the device delivering the impulsive load and subsequent head kinematics rather than performing direct measurement (sensors or videography). The current study therefore examined factors affec...
The AlpArray experiment and the deployment of Swath-D together with the dense permanent network in Italy allow for detailed imaging of the spatio-temporal imaging complexity of seismic wave-fields within the greater Alpine region. The distance of any point within the area to the nearest station is less than 30 km, resulting in an average inter-station distance of about 45 km. With a much denser deployment in a smaller region o...