Translation modifications, particularly those involving histone deacetylases (HDACs), are crucial for regulating gene expression and have significant implications for cardiovascular disease (CVD). The association between HDACs and CVD has garnered significant research interest due to the pivotal role of HDACs in gene expression regulation and cellular function. Aberrant HDAC activity has been implicated in various pathological...

Background Aberrant expression of histone deacetylases (HDACs) and ribonucleotide reductase (RR) enzymes are commonly observed in various cancers. Researchers are focusing on these enzymes in cancer studies with the aim of developing effective chemotherapeutic drugs for cancer treatment. Targeting both HDAC and RR simultaneously with a dual HDAC/RR inhibitor has exhibited enhanced effectiveness compared to monotherapy in cance...

A landslide susceptibility map (LSM) assists in reducing the danger of landslides by locating the landslide-prone locations within the designated area. One of the locations that are prone to landslides in India's Western Ghats of which Goa is a part. This article presents the LSMs prepared for the state of Goa using four standard machine learning algorithms, namely Logistic Regression (LR ), Support Vector Machine (SVM), K -Ne...