This study identifies amide proton transfer (APT) imaging radiomic features that correlate with glioblastoma survival and explore the relationship of combined radiomic data and biomarkers such as age and MGMT methylation status to survival prognosis. In a retrospective study of 66 glioblastoma patients (2022–2023), SlicerBrats was used for automatic tumor segmentation and 504 radiomic features were extracted from APT images. A...

Coastal managers worldwide must prepare for changes in annual wave overtopping events due to climate change and sea-level rise. Research often assesses overtopping discharges by extreme events at a sea wall crest, typically using data from physical models or empirical rules based on scaled experiments. Here, we analyse a unique 1-year field dataset of coastal wave overtopping, from SW England, to determine the number of indivi...

Decomposition is one of several controls on carbon storage in seagrass meadows, but the relative importance of environmental conditions and seagrass species identity in driving decomposition is unclear. We first investigated direct environmental effects on decomposition by measuring percent mass lost of standardized litter, green and rooibos (red) tea, incubated in meadows spanning a naturally occurring phosphorus gradient for...

Climate‐driven shifts in herbivores, temperature, and nutrient runoff threaten coastal ecosystem resilience. However, ecological resilience, particularly for foundation species, remains poorly understood due to the scarcity of field experiments conducted across appropriate spatial and temporal scales that investigate multiple stressors. This study evaluates the resilience of a widespread tropical marine plant (turtlegrass) to...

Artificial Intelligence (AI) based auto-segmentation has demonstrated numerous benefits to clinical radiotherapy workflows. However, the rapidly changing regulatory, research, and market environment presents challenges around selecting and evaluating the most suitable solution. To support the clinical adoption of AI auto-segmentation systems, Selection Criteria recommendations were developed to enable a holistic evaluation of...

Prostate cancer is a significant global health issue due to its high incidence and poor outcomes in metastatic disease. This study aims to develop models predicting overall survival for patients with metastatic biochemically recurrent prostate cancer, potentially helping to identify high-risk patients and enabling more tailored treatment options. A multi-centre cohort of 180 such patients underwent [ 68 Ga]Ga-PSMA-11 PET/CT sc...

Cancer stem cells play an important role in tumor progression and chemotherapy resistance. Leucine-rich G repeat-containing protein-coupled receptor 5 (LGR5) has been identified as a cancer stem cell marker in several cancer types. LGR5 is involved in cancer development and progression via several pathways including WNT/β-catenin signaling pathway. LGR5 plays a role in tumor progression by promoting cancer cell migration, inva...

Marine environments are highly heterogeneous, varying across scales of a few meters to entire ocean basins. Understanding the relationship between environmental variability and species distribution is essential for area‐based management and conservation. However, this requires a precise alignment of seabed mapping with environmental and biological sampling, which is often difficult to achieve in the deep sea. There is thus an...

Motivation Freshwater ecosystems have been heavily impacted by land‐use changes, but data syntheses on these impacts are still limited. Here, we compiled a global database encompassing 241 studies with species abundance data (from multiple biological groups and geographic locations) across sites with different land‐use categories. This compilation will be useful for addressing questions regarding land‐use change and its impact...

Natural shorelines provide ecosystem services that are integral to maintaining healthy and resilient coastal ecosystems and communities. However, anthropogenic and environmental stressors are reducing the extent of natural shorelines, and thus, their capacity to provide critical ecosystem services. Unfortunately, the most common shoreline management strategies involve hardened structures (e.g., bulkheads and seawalls) that are...

Insurance serves modern society and commerce by pooling risk to reduce the economic impact of disasters. Concurrently, Disaster Risk Management (DRM) scientists, responders and policymakers are co-developing proactive resilience and mitigation strategies with European citizens against accelerating climate-related natural catastrophes. The increasing frequency and severity of natural catastrophes exacerbates the insurance cover...