Cortical and deep brain topography are core components of undergraduate neuroanatomy teaching and neurosurgical training. Due to the technical challenges associated with dissecting and maintaining preserved brains, deep white matter preparations are often omitted from anatomy curricula. This reduced opportunity for tactile neuroanatomical exploration contributes to surface-level approaches to learning and is associated with po...

Mutations in LRRK2 are currently recognized as the most common monogenetic cause of Parkinsonism. The elevation of kinase activity of LRRK2 that frequently accompanies its mutations is widely thought to contribute to its toxicity. Accordingly, many groups have developed LRRK2-specific kinase inhibitors as a potential therapeutic strategy. Given that protein phosphorylation is a reversible event, we sought to elucidate the phos...