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On-Demand Hospital Manufacturing of Baclofen Lozenges Using Pharmaceutical 3D PrintingNARA Subscribed
Purpose Dysphagia in neurological patients complicates oral drug administration. Manual preparation of lozenges/troches lacks precision and scalability. This study investigates the feasibility of implementing a pharmaceutical 3D printer in a hospital pharmacy for the automated production of personalized baclofen troches. Methods Baclofen troches were manufactured in a hospital pharmacy setting, both manually and via pharmaceut...
Evaluation of Downscaled CMIP6 Performance for Rainfall and Wind Over the Maritime ContinentNARA Subscribed
High‐resolution climate change projections over the Maritime Continent (MC) are increasingly critical to develop climate policies and adaptation planning at the regional level. However, modelling rainfall and wind over the MC still leads to substantial errors in capturing climate processes over the most complex land–atmosphere–ocean interaction. This study evaluated the performance of the 14 downscaled CMIP6 models from the NA...
Technical pen-based printhead for high-precision microdosing of personalized therapiesNARA Subscribed
Additive manufacturing offers unprecedented opportunities for personalized medicine, but most pharmaceutical printing platforms are optimized for milligram-range doses, limiting their suitability for microdosing. This work introduces a novel liquid deposition approach using a modified technical pen integrated into a pharmaceutical printer. The gravity-driven mechanism enabled precise microscale dispensing without external ther...