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An adaptive two-grid preconditioner and linearly implicit scheme for shale gas transport in fractured porous mediaNARA Subscribed
We consider a nonlinear mixed-dimensional model for simulating gas transport in shale formation. The mathematical model consists of a coupled system of nonlinear equations, where flow within fractures is represented using a lower-dimensional representation. For the numerical solution of the coupled transport problem, we construct an unstructured mesh that resolves lower dimensional fractures on the grid level and use the finit...
The Atlantic Meridional Overturning Circulation (AMOC) redistributes heat, salt, oxygen, carbon, and nutrients in the Atlantic Ocean, providing warmth and moisture to the climate of northern Europe (Rhines and Häkkinen, 2003), displacing the Intertropical Convergence Zone northward of the equator (Ben-Yami et al., 2024), sequestering anthropogenic carbon in the deep ocean (Brown et al., 2021), and seeding the subpolar North At...
Androgen induces 3′UTR shortening of de novo lipogenesis genes by alternative polyadenylation in prostate cancer cellsNARA Subscribed
Alternative polyadenylation (APA) is a pervasive mechanism that is emerging as a formidable player in post-transcriptional regulation. The transcriptional landscape can be altered via APA in response to various stimulating factors. Using the PacBio single-molecule long-read sequencing method, we present for the first time the 3′UTR landscape and reveal a global increase of APA events in prostate cancer (PCa) LNCaP cells in res...
Can procuratorial agencies play a key role in China’s governance of marine plastic pollution (MPPG)? Within the current discussions about the legal framework of China’s MPPG, courts, marine environmental regulatory authorities, procuratorial agencies, and environmental protection organizations are typically seen as the main stakeholders. However, the role of procuratorial agencies, as the statutory entity for initiating PIL in...