Advanced in vitro models are becoming increasingly popular over traditional monolayer cell culture models as they more closely recapitulate key morphological and biochemical aspects of tissue similar to what is found in vivo. Although it is primarily used in disease modelling and drug discovery, the use of these models is expanding into clinical applications as well, including in the field of advanced ocular in vitro models. T...

Traumatic brain injury (TBI) is caused by an external mechanical force to the head, resulting in abnormal brain functioning and clinical manifestations. Antisecretory factor (AF16) is a potential therapeutic agent for TBI treatment due to its ability to inhibit fluid secretion and decrease inflammation, intracranial pressure, and interstitial fluid build-up, key hallmarks presented in TBI. Here, we investigated the effect of A...