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The integration of palaeolimnology into conservation practice is crucial for effective ecosystem management and restoration. Palaeoecological data provide a unique long-term perspective on key ecological challenges and enable decision makers to better understand pre-disturbance conditions, natural system dynamism and responses to change. Despite this there exist well-recognised accessibility issues and a clear research-impleme...
Dominance and rarity in tree communities across the globe: Patterns, predictors and threatsNARA Subscribed
Aim Ecological and anthropogenic factors shift the abundances of dominant and rare tree species within local forest communities, thus affecting species composition and ecosystem functioning. To inform forest and conservation management it is important to understand the drivers of dominance and rarity in local tree communities. We answer the following research questions: (1) What are the patterns of dominance and rarity in tree...
Septic arthritis is a serious condition with significant morbidity and mortality, routinely diagnosed using culture. The FDA has recently approved the rapid molecular BioFire® Joint Infection Panel (BJIP) for synovial fluid. We aimed to evaluate the BJIP compared to culture and its potential use in patient management. A multicentre retrospective evaluation of BJIP was conducted in the UK and Ireland. Positive percent agreement...
We evaluate a 12-member perturbed parameter ensemble of regional climate simulations over Europe at 12 km resolution, carried out as part of the UK Climate Projections (UKCP) project. This ensemble is formed by varying uncertain parameters within the model physics, allowing uncertainty in future projections due to climate modelling uncertainty to be explored in a systematic way. We focus on present day performance both compare...
Untangling local and remote influences in two major petrel habitats in the oligotrophic Southern OceanNARA Subscribed
Ocean circulation connects geographically distinct ecosystems across a wide range of spatial and temporal scales via exchanges of physical and biogeochemical properties. Remote oceanographic processes can be especially important for ecosystems in the Southern Ocean, where the Antarctic Circumpolar Current transports properties across ocean basins through both advection and mixing. Recent tracking studies have indicated the exi...
Deafness, the most frequent sensory deficit in humans, is extremely heterogeneous with hundreds of genes involved. Clinical and genetic analyses of an extended consanguineous family with pre-lingual, moderate-to-profound autosomal recessive sensorineural hearing loss, allowed us to identify CLRN2, encoding a tetraspan protein, as a new deafness gene. Homozygosity mapping followed by exome sequencing identified a 14.96 Mb locus...
Towards quantifying uncertainty in transient climate changeNARA Subscribed