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Synthetic, Population-Based Virtual Patient Database Using a Digital Twin of the Cardiovascular SystemNARA Subscribed
Purpose The goal is to develop a cardiovascular virtual patient database (VPD) combining physiological and demographic data to provide the foundation for future applications in medical diagnostics, decision-making, credibility testing, and formal uncertainty analysis, and to enable its integration with three-dimensional (3D) hemodynamic models and to train neural networks. Methods We generate an initial VPD by treating input p...
Amplification of Secondary Flow at the Initiation Site of Intracranial Sidewall AneurysmsNARA Subscribed
Purpose The initiation of intracranial aneurysms has long been studied, mainly by the evaluation of the wall shear stress field. However, the debate about the emergence of hemodynamic stimuli still persists. This paper builds on our previous hypothesis that secondary flows play an important role in the formation cascade by examining the relationship between flow physics and vessel geometry. Methods A composite evaluation frame...
Hydrodynamic Resistance of Intracranial Flow-Diverter Stents: Measurement Description and Data EvaluationNARA Subscribed
Purpose Intracranial aneurysms are malformations forming bulges on the walls of brain arteries. A flow diverter device is a fine braided wire structure used for the endovascular treatment of brain aneurysms. This work presents a rig and a protocol for the measurement of the hydrodynamic resistance of flow diverter stents. Hydrodynamic resistance is interpreted here as the pressure loss versus volumetric flow rate function thro...
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