Background Controlled laboratory studies have demonstrated that breaking up sitting can reduce postprandial glucose in South Asian adults. This study examined the effects of substituting sitting with standing and walking on interstitial glucose in South Asian individuals under free-living conditions. Methods South Asian adults ( n = 14 [50% male]; body mass index 26.5 ± 0.8 kg·m −2 ) aged 41 ± 3 years completed two, 4-day regi...