Fish‐derived antimicrobial peptides are an important part of the innate immune system due to their potent antimicrobial properties. Piscidins are a class of antimicrobial peptides first described in hybrid striped bass ( Morone chrysops x Morone saxatilis ) but have also been identified in many other fish species. Previous work demonstrated the broad antimicrobial activity of piscidins against Gram‐negative and Gram‐positive b...