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Springer Nature1
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Clinical & Experimental Metastasis1
Publication Year
20261
Benjamin Troness results 1 · Newest (Page 1/1, per page 25)
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Modeling the role of urokinase-type plasminogen activator, uPA, and circulating cancer-associated fibroblasts (cCAFs) in breast cancer cell extravasationNARA Subscribed
Clinical & Experimental Metastasis · 2026 · Vol. 43 · Issue 3 · Springer
Angela Spartz; Susan Schmidt; Fazila Mohamed; Benjamin Troness; Carol A. Lange; Dorraya El-Ashry
Circulating Cancer-Associated Fibroblasts (cCAFs) have been identified in circulating tumor cell clusters from all stages of disease progression in breast cancer patients. We have shown that CAFs promote lung metastases in the mouse tail vein model when they are clustered with triple negative breast cancer (TNBC) MDA-MB231 cells. Following on this observation, we saw that MDA-MB231-luciferase labeled cells persist at higher le...
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