Bernd Herrmann results 13
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Genotoxicity assessment: opportunities, challenges and perspectives for quantitative evaluations of dose–response dataNARA Subscribed
Genotoxicity data are mainly interpreted in a qualitative way, which typically results in a binary classification of chemical entities. For more than a decade, there has been a discussion about the need for a paradigm shift in this regard. Here, we review current opportunities, challenges and perspectives for a more quantitative approach to genotoxicity assessment. Currently discussed opportunities mainly include the determina...
Enhancement of Immunosuppressive Activity of Mesenchymal Stromal Cells by Platelet-Derived Factors is Accompanied by Apoptotic PrimingNARA Subscribed
The pro-inflammatory phase of bone healing, initiated by platelet activation and eventually hematoma formation, impacts bone marrow mesenchymal stromal cells (MSCs) in unknown ways. Here, we created platelet-rich plasma (PRP) hydrogels to study how platelet-derived factors modulate functional properties of encapsulated MSCs in comparison to a non-inflammatory fibrin (FBR) hydrogel environment. MSCs were isolated from human bon...
Key message Three independent experiments with different genetic backgrounds mapped the resistance gene Pm7 in the oat genome to the distal part of the long arm of chromosome 5D. Abstract Resistance of oat to Blumeria graminis DC. f. sp. avenae is an important breeding goal in Central and Western Europe. In this study, the position of the effective and widely used resistance gene Pm7 in the oat genome was determined based on t...
This study investigated the efficiency of a sieve‐panel concept, intended to separate bycatch species from Nephrops (Norway lobster) in a trawl gear via mechanical and behavioural means. Four different designs of varying panel mesh size or inclination were tested in experimental fishing. For each design, the length‐dependent sieving efficiency, defined as the fraction of Nephrops or fish passing through the panel to the lower...
P-V-T behavior of FeO(OH) and MnO(OH)NARA Subscribed
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