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Rapid quantification method of pharmaceuticals in urban wastewater using UHPLC-Orbitrap mass spectrometry—a multi-target approach for EU-directive advanced treatment evaluationNARA Subscribed
Naunyn-Schmiedeberg's Archives of Pharmacology · 2026 · Vol. 399 · Issue 11 · Springer
Uta Hofmann; Reinhard Oertel; Nancy Engel; Johannes Zander; Annemarie Lippert; Sara Schubert; Bertold Renner
Pharmaceutical residues have become micropollutants of emerging concern in wastewater. Insufficient removal by wastewater treatment plants (WWTPs) can result in negative ecotoxicological impacts on aquatic ecosystems. Therefore, the EU Urban Wastewater Treatment Directive (UWWTD 2024/3019) requires quaternary treatment upgrades and regular monitoring in European wastewater treatment plants. This necessitates efficient and easy...
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In memory of Professor Dr. med. Dr. h. c. Kay Brune (1941–2025), Past President of the German Society for Experimental and Clinical Pharmacology and Toxicology and honorary member of the German Society for PharmacologyNARA Subscribed
Naunyn-Schmiedeberg's Archives of Pharmacology · 2026 · Vol. 399 · Issue 5 · Springer
Burkhard Hinz; Bertold Renner; Gerd Geisslinger
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Drug consumption in German cities and municipalities during the COVID-19 lockdown: a wastewater analysisNARA Subscribed
Naunyn-Schmiedeberg's Archives of Pharmacology · 2023 · Vol. 396 · Issue 5 · Springer
Reinhard Oertel; Sara Schubert; Björn Helm; Robin Mayer; Roger Dumke; Ali El-Armouche; Bertold Renner
Analysis of illicit drugs, medicines, and pathogens in wastewater is a powerful tool for epidemiological studies to monitor public health trends. The aims of this study were to (i) assess spatial and temporal trends of population-normalized mass loads of illicit drugs and nicotine in raw wastewater in the time of regulations against SARS-CoV-2 infections (2020–21) and (ii) find substances that are feasible markers for characte...
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Regional and temporal differences in the relation between SARS-CoV-2 biomarkers in wastewater and estimated infection prevalence – Insights from long-term surveillanceNARA Subscribed
Science of The Total Environment · 2023 · Vol. 857 · Elsevier
Björn Helm; Michael Geissler; Robin Mayer; Sara Schubert; Reinhard Oertel; Roger Dumke; Alexander Dalpke; Ali El-Armouche; Bertold Renner; Peter Krebs
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N1-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin–trimethoprim interactionNARA Subscribed
European Journal of Clinical Pharmacology · 2015 · Vol. 71 · Issue 1 · Springer
Fabian Müller; Constanza A. Pontones; Bertold Renner; Maren Mieth; Eva Hoier; Daniel Auge; Renke Maas; Oliver Zolk; Martin F. Fromm
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Tonic stimulation of the pharyngeal mucosa causes pain and a reversible increase of inflammatory mediatorsNARA Subscribed
Inflammation Research · 2013 · Vol. 62 · Issue 12 · Springer
Bertold Renner; Gabi Ahne; Elke Grosan; Birgit Kettenmann; Gerd Kobal; Adrian Shephard
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Environmental and non-infectious factors in the aetiology of pharyngitis (sore throat)NARA Subscribed
Inflammation Research · 2012 · Vol. 61 · Issue 10 · Springer
Bertold Renner; Christian A. Mueller; Adrian Shephard
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Olfactory and trigeminal interaction of menthol and nicotine in humansNARA Subscribed
Experimental Brain Research · 2012 · Vol. 219 · Issue 1 · Springer
Bertold Renner; Karen Schreiber
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Absorption and distribution of etoricoxib in plasma, CSF, and wound tissue in patients following hip surgery—a pilot studyNARA Subscribed
Naunyn-Schmiedeberg's Archives of Pharmacology · 2010 · Vol. 381 · Issue 2 · Springer
Bertold Renner; Josef Zacher; Asokumar Buvanendran; Gerrit Walter; Jochen Strauss; Kay Brune
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Population Pharmacokinetics of Fast Release Oral Diclofenac in Healthy Volunteers: Relation to Pharmacodynamics in an Experimental Pain ModelNARA Subscribed
Pharmaceutical Research · 2000 · Vol. 17 · Issue 1 · Springer
Jörn Lötsch; Birgit Kettenmann; Bertold Renner; David Drover; Kay Brune; Gerd Geisslinger; Gerd Kobal
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