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Springer Nature1
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Naunyn-Schmiedeberg's Archives of Pharmacology1
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20261
Birgit Klampe results 1 · Newest (Page 1/1, per page 25)
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Author: Birgit Klampe ×Clear All Filters
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Positive inotropic effects of serotonin in atrial EHT: further proof for an atrial phenotype?NARA Subscribed
Naunyn-Schmiedeberg's Archives of Pharmacology · 2026 · Vol. 399 · Issue 4 · Springer
Muhammed Sönmez; Margaret Nandudu; Paul Brunnbauer; Carl Schulz; Birgit Klampe; Thomas Schulze; Arne Hansen; Thomas Eschenhagen; Torsten Christ
Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) cultured in the presence of retinoic acid were proposed as a model for human atrium. Since in the human heart positive inotropic effects of serotonin (5-HT) are restricted to the atrium, we investigated whether the presence of 5-HT responses may distinguish between hiPSC-atrial and ventricular CM. Nonfiltered retinoic acid (1 µM) was used to induce an atrial...
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