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Antineoplastic therapy affects the in vitro phenotype and functionality of healthy human bone marrow-derived mesenchymal stromal cellsNARA Subscribed
While antineoplastic therapies aim to specifically target cancer cells, they may also exert adverse effects on healthy tissues, like healthy hematopoietic stem and progenitor cells (HSPC), leading to hematotoxicity as a common side effect. Mesenchymal stromal cells (MSC) are a major component of the bone marrow (BM) microenvironment, regulating normal hematopoiesis, while their susceptibility to anticancer therapies and contri...
Accounting for nutrition-related health impacts in food life cycle assessment: insights from an expert workshopNARA Subscribed
Sub-optimal dietary patterns make major contributions to the Global Burden of Disease and are among the most pressing issues affecting human health. Consequently, they are key to consider when assessing the human health and other environmental impacts of foods and diets within life cycle assessments. The UN Environment Life Cycle Initiative convened a task force on nutrition-related human health impacts as part of the Global L...
Tree diversity enhances predation by birds but not by arthropods across climate gradientsNARA Subscribed
Tree diversity can promote both predator abundance and diversity. However, whether this translates into increased predation and top‐down control of herbivores across predator taxonomic groups and contrasting environmental conditions remains unresolved. We used a global network of tree diversity experiments ( TreeDivNet ) spread across three continents and three biomes to test the effects of tree species richness on predation a...
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