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The natural history and genotype–phenotype correlations of TMPRSS3 hearing loss: an international, multi-center, cohort analysisNARA Subscribed
TMPRSS3 -related hearing loss presents challenges in correlating genotypic variants with clinical phenotypes due to the small sample sizes of previous studies. We conducted a cross-sectional genomics study coupled with retrospective clinical phenotype analysis on 127 individuals. These individuals were from 16 academic medical centers across 6 countries. Key findings revealed 47 unique TMPRSS3 variants with significant differe...
Mentoring is suggested as an important strategy to promote workplace inclusivity and is shown to be positively associated with high employee morale, yet mentee needs and experiences may not be universal. To evaluate mentoring impacts from the perspective of USDA Forest Service employees, we conducted an online survey of 251 aquatic professionals, including managers and scientists. 70% of respondents had mentors, and mentorship...
One of the most fundamental yet challenging tasks for aquatic ecologists is to precisely delineate the range of species, particularly those that are broadly distributed, require specialized sampling methods, and may be simultaneously declining and increasing in different portions of their range. An exemplar is the Pacific lamprey Entosphenus tridentatus , a jawless anadromous fish of conservation concern that is actively manag...
Population Viability Analysis of Spring Chinook Salmon in the South Umpqua River, OregonNARA Subscribed
Run sizes of spring chinook salmon in the South Umpqua River in Oregon have declined dramatically since the early part of this century. Habitat degradation is thought to be an important factor contributing to the decline of this stock, and qualitative assessment suggests the stock is at moderate risk of extinction. We use data from this and similar stocks to develop an age‐structured, density‐dependent model of the population...
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