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Impact of gelatin supplementation on indices of skeletal muscle recovery: a pilot studyNARA Subscribed
Purpose This pilot study examined whether collagen supplementation, via gelatin, influences indices of skeletal muscle recovery following strenuous exercise. Methods Using a double-blind, randomized, placebo-controlled design, recreationally-active adults (25.9 ± 4.6 yrs.; 11 F, 11 M) consumed gelatin (GEL; 15 g) or placebo (PLA) twice daily. Participants performed 150 maximal unilateral eccentric knee extensions. Muscle soren...
Objective This study investigated how cumulative environmental exposures influence offspring behaviour and inflammation-related molecular signatures in the brain and peripheral immune system. Methods A novel "triple-hit" mouse model was developed using C57Bl/6JAusB mice (N = 70), combining preconceptual social stress, antenatal high-fat diet, and a postnatal immune challenge (poly(I:C), 10 mg/kg). At 12 weeks, offspring underw...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Beneath the Surface: Mental Health in Commercial FisheriesNARA Subscribed
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
Balancing boat‐electrofishing sampling effort against costs for nearshore fish communities in the Toronto waterfront, Lake OntarioNARA Subscribed
To enhance management of aquatic systems, long‐term monitoring programs are crucial. However, managers often lack sufficient guidance in decision‐making. In this study, we analyzed nearshore electrofishing data from Lake Ontario spanning 18 years and over 100,000 caught fish to assess sampling designs for various coastal habitats. Using simulation, we evaluated precision of catch per unit effort (CPUE) for all species, piscivo...
Inhibition of the target of rapamycin (TOR/mTOR) protein kinase by the drug rapamycin extends lifespan and health span across diverse species. However, rapamycin has potential off-target and side effects that warrant the discovery of additional TOR inhibitors. TOR was initially discovered in Saccharomyces cerevisiae (yeast) which contains two TOR paralogs, TOR1 and TOR2 . Yeast lacking functional Tor1 are viable but are hypers...
Like many forage fish species, Pacific sand lance ( Ammodytes personatus ) play a key role in nearshore marine ecosystems as an important prey source for a diverse array of predators in the northeastern Pacific. However, the primary threats to Pacific sand lance and their habitat are poorly defined due to a lack of systematic data. Crucial information needed to assess their population status is also lacking including basic kno...
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed