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Efficacy of an Inactivated Bacterin Vaccine Against Emerging Streptococcus dysgalactiae in Channel Catfish ( Ictalurus punctatus )NARA Subscribed
Lancefield Group C Streptococcus dysgalactiae recently emerged as a catfish pathogen in the US. Reports from hatcheries suggest S. dysgalactiae causes substantial broodfish loss. We aimed to develop a challenge model and evaluate vaccine efficacy against S. dysgalactiae in juvenile channel catfish ( Ictalurus punctatus ). Three S. dysgalactiae (14–1, 14–24 and 14–25) isolates were tested for virulence. Intracoelomic (IC) injec...
Interlaboratory clinical chemistry parameter variation in seven-day acute hydrazine toxicity studies in the Sprague-Dawley ratNARA Subscribed
Clinical chemistry retains its position as a cornerstone of toxicological assessment, yet inter-laboratory variability in baseline values remains a challenge for the integration and interpretation of multisite datasets. This study leveraged a publicly available clinical chemistry database to assess the impact of inter-laboratory variability in response to hydrazine-induced steatosis. Seventeen clinical chemistry and physico-ch...
Quantifying intra-urban socio-economic and environmental vulnerability to extreme heat events in Johannesburg, South AfricaNARA Subscribed
Urban populations face increasing vulnerability to extreme heat events, particularly in rapidly urbanising Global South cities where environmental exposure intersects with socioeconomic inequality and limited healthcare access. This study quantifies heat vulnerability across Johannesburg, South Africa, by integrating high-resolution environmental data with socio-economic and health metrics across 135 urban wards. We examine ho...
An Overview of Vaccine Development Strategies for Columnaris‐Causing Bacteria in Cultured FishNARA Subscribed
Columnaris disease, caused by columnaris‐causing bacteria (CCB), affects cultured and wild freshwater fish worldwide. Belonging to the phylum Bacteroidota and the family Flavobacteriaceae, CCB are gram‐negative, yellow‐pigmented bacteria that are presumed ubiquitous in freshwater habitats. Since the first report of the disease in 1922, growth and survival, pathogenesis, and transmission of these pathogens have been intensely r...
Identifying and assessing the magnitude of direct threats to ecosystems and species are critical steps to prioritizing, planning, implementing, and assessing conservation actions. Just as medical clinicians and researchers need a standard way to talk about human diseases, conservation practitioners and scientists need a common and comprehensive language to talk about the threats they are facing to facilitate joint action, eval...
Channel catfish ( Ictalurus punctatus ) and Nile tilapia ( Oreochromis niloticus ) are two aquaculture species of great importance. Intensive production is often hindered by poor growth performance and disease mortality. The aim of this study was to evaluate the potential of a commercial fermented yeast product, DVAQUA, on channel catfish and Nile tilapia growth performance metrics and disease resistance. Channel catfish and N...
Probiotics enhance resistance to Streptococcus iniae in Nile tilapia ( Oreochromis niloticus ) reared in biofloc systemsNARA Subscribed
Biofloc technology is a rearing technique that maintains desired water quality by manipulating carbon and nitrogen and their inherent mixture of organic matter and microbes. Beneficial microorganisms in biofloc systems produce bioactive metabolites that may deter the growth of pathogenic microbes. As little is known about the interaction of biofloc systems and the addition of probiotics, this study focused on this integration...
Husk spot caused by the Pseudocercospora macadamiae fungus induces premature abscission of fruit in many industry standard macadamia cultivars. Fungicides and other management strategies add to farm costs, thus breeding for varietal resistance is important. Genetic parameters of husk spot symptom expression had not previously been estimated. To guide selection methods for field resistance, over 300 open-pollinated seedlings of...
Drivers of 20th century sea‐level change in southern New Zealand determined from proxy and instrumental recordsNARA Subscribed
In this paper we present new proxy‐based sea‐level reconstructions for southern New Zealand spanning the last millennium. These palaeo sea‐level records usefully complement sparse Southern Hemisphere proxy and tide‐gauge sea‐level datasets and, in combination with instrumental observations, can test hypotheses about the drivers of 20th century global sea‐level change, including land‐based ice melt and regional sterodynamics. W...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...