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Tracing population structure and dispersal of planktonic organisms is a challenging yet crucial task, as it helps identify how populations are connected across regions, detect isolated or vulnerable populations and anticipate how human-driven changes in ocean may alter these dynamics. Here, we used the top predator Cyanea capillata , a bloom-forming jellyfish, as a target organism since its population structure, dispersal and...
Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. A steep rise in AD incidents is observed in the elderly population in East-Asian countries. The disease progresses through several changes, including memory loss, behavioural issues, and cognitive impairment. The etiology of AD is hard to determine because of its complex nature. The whole exome se...
Molecular phylodynamics of infectious bursal disease virusesNARA Subscribed
In vitro screening for pharmacological activity of existing drugs showed chloroquine and hydroxychloroquine to be effective against severe acute respiratory syndrome coronavirus 2. Oral administration of these compounds to obtain desired pulmonary exposures resulted in dose-limiting systemic toxicity in humans. However, pulmonary drug delivery enables direct and rapid administration to obtain higher local tissue concentrations...