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Rhabdomyosarcoma (RMS) is a highly aggressive pediatric soft tissue sarcoma with limited therapeutic options, particularly for cases resistant to conventional treatments. The SUMOylation pathway, which plays a key role in regulating the cell cycle, apoptosis, and transcription, has emerged as a potential therapeutic target in RMS. Elevated levels of SUMO1 and SUMO2/3 conjugates in RMS cell lines, compared to normal human skele...
Reconstructing the topography of shallow underwater environments using Structure-from-Motion—Multi View Stereo (SfM-MVS) techniques applied to aerial imagery from Unmanned Aerial Vehicles (UAVs) is challenging, as it involves nonlinear distortions caused by water refraction. This study presents an experiment with aerial photographs collected with a consumer-grade UAV on the shallow-water reef of Fuvahmulah, the Maldives. Under...
Mortality from collision with vehicles is the most visible impact of road traffic on wildlife. Mortality due to roads (hereafter road‐kill) can affect the dynamic of populations of many species and can, therefore, increase the risk of local decline or extinction. This is especially true in Brazil, where plans for road network upgrading and expansion overlaps biodiversity hotspot areas, which are of high importance for global c...
Summary Chemolithoautotrophic bacteria from the genera Hydrogenovibrio, Thiomicrorhabdus and Thiomicrospira are common, sometimes dominant, isolates from sulfidic habitats including hydrothermal vents, soda and salt lakes and marine sediments. Their genome sequences confirm their membership in a deeply branching clade of the Gammaproteobacteria . Several adaptations to heterogeneous habitats are apparent. Their genomes include...
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