C. Fischer results 321
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Population genomics for biodiversity conservation: Insights from the Swiss pilot study for monitoring genetic diversityNARA Subscribed
Genetic diversity is the raw material of evolution and is essential for adaptation and survival. Concerted efforts have been made under the Kunming-Montreal Global Biodiversity Framework (GBF) to incorporate intraspecific genetic diversity into national monitoring efforts. Much emphasis has been put on non-genetic proxies of genetic diversity, due to the limited amount of genetic data currently available on species and their p...
Local and Landscape‐Level Environmental Conditions Drive Habitat Selection Across Terrestrial Mammal SpeciesNARA Subscribed
Aim Animal movements are a fundamental process affecting communities and ecosystems. Quantifying habitat selection across species and habitats is key for understanding how animals respond to environmental change. Currently, we lack comparative studies that examine how habitat selection varies across species traits and landscapes. We aim to quantify global patterns of habitat selection to help understand the fundamental drivers...
The Impact of Pleistocene Glacial Cycles on the Evolutionary Diversification of the Arctic‐Alpine Silene acaulis Species ComplexNARA Subscribed
Arctic‐alpine species are highly sensitive to long‐term temperature changes and associated glacial cycles due to their occurrence in cold environments to which they are adapted and spatially restricted. Unravelling their evolutionary responses to past climatic fluctuations can provide new insights into their diversification. In this study, we investigated the evolutionary history of the Silene acaulis species complex and how i...
Pelagic sharks target long‐lived, retentive anticyclonic eddies in the Northwest Atlantic OceanNARA Subscribed
Open ocean ecosystems represent the largest habitat on Earth and are highly dynamic in time and space. Mesoscale eddies are a primary driver of this variability and serve a key structural role in ocean ecosystems. Eddies modulate marine biodiversity beyond their impacts on plankton, influencing many ecologically and commercially important predators that may preferentially occupy anticyclonic eddies. However, how animal‐eddy in...
Combining Observations and Models: A Review of the CARDAMOM Framework for Data‐Constrained Terrestrial Ecosystem ModelingNARA Subscribed
The rapid increase in the volume and variety of terrestrial biosphere observations (i.e., remote sensing data and in situ measurements) offers a unique opportunity to derive ecological insights, refine process‐based models, and improve forecasting for decision support. However, despite their potential, ecological observations have primarily been used to benchmark process‐based models, as many past and current models lack the c...
Introduction of immune checkpoint inhibitors (ICI) has improved overall survival (OS) for advanced non-small cell lung cancer (NSCLC). However, responses differ greatly amongst patients. Additional radiotherapy (RT) may promote tumor-specific immunity and synergize with ICI to improve tumor control. The multicenter phase II FORCE trial evaluated safety and efficacy of nivolumab with additional palliative radiotherapy (5 × 4 Gy...
A physically and mentally active lifestyle relates to younger brain and cognitive ageNARA Subscribed
Resistance to age-related pathological changes (brain maintenance), including Alzheimer’s disease, cerebrovascular disease, and neurodegeneration may promote cognitive resilience in aging. However, how lifestyle and health profiles relate to successful cognitive and brain aging remains poorly understood. In a novel, deeply phenotyped cohort of 211 cognitively unimpaired older adults (age = 71.0 ± 7.4 years, 46% female), we cha...