We evaluated endolithic fungal diversity associated with rocks sampled at the polyextreme Brazilian São Pedro and São Paulo archipelago using a DNA amplicon metagenomics approach. We detected 808,547 fungal DNA reads grouped into 92 amplicon sequence variants (ASVs). The rocks sampled were geologically characterized as mylonitized peridotites, serpentinized peridotites, and carbonate-matrix sedimentary breccias. Ascomycota was...

Increasing life expectancy has been accompanied by a higher prevalence of age-associated conditions, underscoring the need to better understand biological mechanisms of aging and to identify accessible biomarkers. Extracellular vesicles (EVs) are lipid-bilayer vesicles that mediate intercellular communication by transporting proteins, lipids, and regulatory RNAs, including microRNAs (miRNAs). Here, we investigated whether the...

This study documents the lifecycle and large-scale environment of a large-hail producing supercell that occurred in southern Brazil (SB) on 6 October 2015. The supercell underwent a merger with a nascent supercell near a Doppler weather radar and rapidly intensified shortly after the interaction. The original (premerger) supercell developed in a high-shear, high-instability pre-cyclogenesis environment and remained isolated un...

Biometals such as iron, copper, zinc, manganese, cobalt, and selenium play crucial roles in cellular respiration, immunity, apoptosis, and signaling. However, their excessive accumulation can induce chronic inflammation, oxidative stress, and trigger carcinogenesis. Iron addiction stands out for its importance in tumor cell replication and survival. Cancer remains one of the leading causes of mortality worldwide. Given the lim...

Predicting permeability from Nuclear Magnetic Resonance (NMR) data is a fundamental yet challenging task in reservoir characterization, primarily due to the uncertainty associated with surface relaxivity ( $$\rho $$ ρ ) parameters. In this work, we investigate the feasibility of using Machine Learning (ML) to estimate permeability from $$T_2$$ T 2 distributions and quantify how $$\rho $$ ρ uncertainty affects predictive accura...

Clepsammia gaia Chaul & Lopes-Andrade gen. et sp. n. is described herein, representing the first new taxon of Cephaloplectini (Ptiliidae) proposed in more than 80 years. The species is blind and flightless, as are all other known members of the tribe, but it exhibits a highly distinctive morphology, characterized by a conspicuous mid-body constriction bearing spongiform setae. The description is based on five specimens collect...

L-DOPA (LD) is the gold-standard treatment of motor symptoms in Parkinson’s disease (PD), conventionally used to prove the predictive value of PD animal models. This study aimed to investigate the predictive validity of an adaptation of the conventional reserpine model of PD: the repeated low-dose reserpine administration in rodents, which promotes progressive motor impairment in catalepsy, vacuous chewing behavior tests, and...

Along more than 2,500 km of tropical coastline north of Rio de Janeiro, the invasive coral Tubastraea spp. has primarily been observed on shipwrecks and oil platforms located on the outer continental shelf or slope. An exception is Baía de Todos os Santos (BTS), a large estuary near 13°S, where Tubastraea spp . has been repeatedly documented since its first occurrence in 2012. These reports have raised concerns about BTS poten...