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Use of translational fusions to express functional Klebsiella oxytoca dinitrogenase reductase in plant mitochondriaNARA Subscribed
Engineering crop plants with the biological nitrogen fixation pathway is a longstanding goal of modern agriculture. Dinitrogenase reductase (NifH) is a critical component of the biological nitrogen fixation pathway, with multiple roles in metal cofactor assembly and catalysis. This enzyme must be folded correctly as a soluble homodimer and loaded with the [4Fe-4S] metallocluster for function. Previous studies have found that K...
Mechanisms and flexibility in plant asymmetric cell divisionNARA Subscribed
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Bakanae disease of rice has emerged as a major threat in the rice‐growingregions of Eastern and Northeastern India. Under field conditions, Fusarium species associated with bakanae disease of rice exhibit a significant degree of variability. Characterizing the pathogen and its isolates is crucial for understanding this variability. This study aimed to assess the genetic diversity and virulence patterns among 88 Fusarium isolat...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
The Holocene history of Australia's climate is surprisingly poorly understood. This is, in part, because of the relatively weak forcing of Holocene climate versus that of the late Pleistocene. However, it is commonly suggested that eastern Australia dried during the mid‐ to late‐Holocene and that this was in response to increased activity in the El Niño–Southern Oscillation (ENSO), in particular, the intensification of the El...
The odds and costs of ambulance attendances associated with heatwave severity in older adults of queensland, AustraliaNARA Subscribed
Ambulance attendances have been increasingly reported to be a sensitive indicator of increased health service utilisations during heatwaves. This study estimated the odds and costs of ambulance attendances associated with heatwave severity (low-intensity, severe, and extreme) in older adults (≥ 65 years) from 1st January 2010 to 31st December 2018 in the State of Queensland, Australia. The findings showed that low-intensity, s...
Combining Observations and Models: A Review of the CARDAMOM Framework for Data‐Constrained Terrestrial Ecosystem ModelingNARA Subscribed
The rapid increase in the volume and variety of terrestrial biosphere observations (i.e., remote sensing data and in situ measurements) offers a unique opportunity to derive ecological insights, refine process‐based models, and improve forecasting for decision support. However, despite their potential, ecological observations have primarily been used to benchmark process‐based models, as many past and current models lack the c...
Changes in community composition and functional diversity of European bats under climate changeNARA Subscribed
Climate change is predicted to drive geographical range shifts that will result in changes in species diversity and functional composition and have potential repercussions for ecosystem functioning. However, the effect of these changes on species composition and functional diversity (FD) remains unclear, especially for mammals, specifically bats. We used species distribution models and a comprehensive ecological and morphometr...