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Lamin subtype expression in Merkel-cell carcinoma: its relation to polyomavirus infection and tumor metastasisNARA Subscribed
Merkel-cell carcinoma (MCC) is known for its high metastatic potential. Studies in several tumor types have proposed a role for up- or downregulation of nuclear A- and B-type lamins in facilitating the process of invasion and metastasis, but such studies are lacking for MCC. Therefore, lamin expression levels were examined in 38 tissue samples from 28 patients with MCC using immunohistochemistry. The series comprised primary t...
Beyond Climate Change: The Role of Integrated Soil Fertility Management for Sustaining Future Maize Yield in Sub‐Saharan AfricaNARA Subscribed
Climate change is projected to exacerbate food insecurity in sub‐Saharan Africa (SSA) by reducing crop yields and soil fertility. Many climate change impact studies in SSA have overlooked long‐term effects of soil fertility on crop yield. We evaluated maize yields under different scenarios of soil fertility (using soil organic carbon as a proxy) and climate change (considering changes in temperature, rainfall, and CO 2 ) at fo...
Background Cereal crops dominate arable agriculture and underpin global food supply. Cereal grain yield is closely related to crop nitrogen (N) uptake. However, excessive inputs of N fertiliser in cereal production systems can have negative environmental consequences and represent high financial risk for farmers. Scope This review explores opportunities to reduce the current reliance of the global staples, wheat ( Triticum aes...
Genetic mixing in conservation translocations increases diversity of a keystone threatened species, Bettongia lesueurNARA Subscribed
Translocation programmes are increasingly being informed by genetic data to monitor and enhance conservation outcomes for both natural and established populations. These data provide a window into contemporary patterns of genetic diversity, structure and relatedness that can guide managers in how to best source animals for their translocation programmes. The inclusion of historical samples, where possible, strengthens monitori...
Chronic coastal erosion is a recurring issue that threatens the built environment and the stability of public beaches. Dynamic cobble berm revetments, which replicate natural composite beaches, are a possible option for nature-based erosion mitigation on high-energy coastlines. Dynamic cobble berm revetments are composed of a sandy foreshore and an engineered cobble berm, which evolves over time while dissipating wave energy....
Fungal communities are critical for leaf decomposition, a central ecosystem function in streams. A wide range of anthropogenic stressors can alter their structure and function (i.e., leaf decomposition). Additionally, fungal communities are subject to seasonal turnover due to natural processes. Despite this, seasonality in interaction with varying stressor exposure has rarely been studied in the context of leaf decomposition....
Speciation across biomes: Rapid diversification with reproductive isolation in the Australian delicate miceNARA Subscribed
Phylogeographic studies of continental clades, especially when combined with palaeoclimate modelling, provide powerful insight into how environment drives speciation across climatic contexts. Australia, a continent characterized by disparate modern biomes and dynamic climate change, provides diverse opportunity to reconstruct the impact of past and present environments on diversification. Here, we use genomic‐scale data (1310...
Initiation of speciation across multiple dimensions in a rock‐restricted, tropical lizardNARA Subscribed
Population isolation and concomitant genetic divergence, resulting in strong phylogeographical structure, is a core aspect of speciation initiation. If and how speciation then proceeds and ultimately completes depends on multiple factors that mediate reproductive isolation, including divergence in genomes, ecology and mating traits. Here we explored these multiple dimensions in two young (Plio‐Pleistocene) species complexes of...
Emergent aquatic insects constitute an important food source for higher trophic levels, linking aquatic to terrestrial ecosystems. Little is known about how land use affects the biomass or composition of insect emergence. Previous studies are limited to individual time points or seasons, hampering understanding of annual biomass export patterns and detection of phenological changes. Over 1 year's primary emergence period, we c...
We studied the transleaflet coupling of compositionally asymmetric liposomes in the fluid phase. The vesicles were produced by cyclodextrin-mediated lipid exchange and contained dipalmitoyl phosphatidylcholine (DPPC) in the inner leaflet and different mixed-chain phosphatidylcholines (PCs) as well as milk sphingomyelin (MSM) in the outer leaflet. In order to jointly analyze the obtained small-angle neutron and X-ray scattering...
When closely related species come into contact via range expansion, both may experience reduced fitness as a result of the interaction. Selection is expected to favour traits that minimize costly interspecies reproductive interactions (such as mismating) via a phenomenon called reproductive character displacement (RCD). Research on RCD frequently assumes secondary contact between species, but the geographical history of specie...
To determine the drivers of phytoplankton biomass, we collected standardized morphometric, physical, and biological data in 230 lakes across the Mediterranean, Continental, and Boreal climatic zones of the European continent. Multilinear regression models tested on this snapshot of mostly eutrophic lakes (median total phosphorus [TP] = 0.06 and total nitrogen [TN] = 0.7 mg L −1 ), and its subsets (2 depth types and 3 climatic...