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In recent years, machine learning and artificial intelligence approaches have been increasingly applied in the context of toxicological risk assessment. Many published overview, review, and comment papers discuss advantages, disadvantages, success stories, and open challenges for the application of machine learning models in toxicology. Machine learning methods using information from in vitro experiments can help to avoid anim...
Objectives of the study were to determine the success, complication and recurrence rate of endoscopic papillectomies in familial adenomatous polyposis (FAP) patients. Ampullary adenoma is frequent in familial adenomatous polyposis (FAP) patients. Endoscopic papillectomy is technically demanding for laterally spreading ampullary adenomas and bleeding, perforation and pancreatitis represent typical complications. 40 FAP patients...
A balanced approach to the potential of octopus aquacultureNARA Subscribed
Diet Driven Differences in Host Tolerance Are Linked to Shifts in Global Gene Expression in a Common Avian Host‐Pathogen SystemNARA Subscribed
Wildlife have become increasingly dependent on anthropogenic resources, altering interactions between individuals and subsequently disease transmission. Further, nutritional quantity and quality impact an individual's ability to mitigate damage caused by infectious disease. Thus, understanding how diet affects immune function is critical for predicting disease severity and transmission. Here, we use transcriptomics to explore...
Life‐history parameters of adult females of Merluccius capensis ( Gadidae ) off the south coast of South AfricaNARA Subscribed
This study explores the life‐history parameters of female Merluccius capensis off South Africa ( N = 1819) during 2014–2016, including gonadosomatic index (GSI), length‐at‐maturity, length–weight relationships, and condition indices (relative condition [ k ] and Fulton's condition factor [ K ]). We detected weak indications of two peaks of spawning within the year, the first in austral autumn from March to May, whereas the oth...
Rationale Cannabidiol (CBD) and cannabidiolic acid (CBDA) are non-psychoactive components of the cannabis plant. CBD has been well characterised to have anxiolytic and anticonvulsant activity, whereas the behavioural effects of CBDA are less clear. Preclinical and clinical data suggests that CBD has antipsychotic properties and reduces methamphetamine self-administration in rats. An animal model that is commonly used to mimic...
World Octopus FisheriesNARA Subscribed
The carrot psyllid Trioza apicalis Förster 1848 is a carrot pest in Europe that can cause serious damages in case of massive occurrence. Damages up to a total loss of yield have been reported from Scandinavian countries but also from Switzerland. The action threshold to control the pest with chemical pesticides is 0.2 T. apicalis per day and trap caught by sticky traps. We investigated the number of T. apicalis with sticky tra...
A synthesis of patterns of environmental mercury inputs, exposure and effects in New York StateNARA Subscribed
Mercury (Hg) pollution is an environmental problem that adversely affects human and ecosystem health at local, regional, and global scales—including within New York State. More than two-thirds of the Hg currently released to the environment originates, either directly or indirectly, from human activities. Since the early 1800s, global atmospheric Hg concentrations have increased by three- to eight-fold over natural levels. In...