C. Walker results 416
· Newest (Page 1/17, per page 25)
Author: C. Walker ×Clear All Filters
Search Results
Motivation The database initiated by the Mountain Invasion Research Network (MIREN) is one of the few globally implemented standardized vegetation surveys in mountains. The focus is on collecting plant species occurrences at 5‐year intervals along and adjacent to mountain roads spanning elevational gradients, with the goal of providing critical information about the ongoing spread of non‐native plants and the potential impacts...
Regulatory Responses of Ectothermic Embryos to Predicted Heat Stresses Under Near‐Future Climate ChangeNARA Subscribed
Heat stress can disrupt coordinated regulatory processes underpinning normal development, resulting in embryonic malformation and inviability. Embryonic buffering against thermal challenge may therefore play a crucial role in individual survival and population resilience under heat stress. Yet, the molecular mechanisms underpinning embryonic defence against ecologically‐meaningful heat stresses remain poorly understood. We inv...
Output from dynamically downscaled, convection‐permitting regional climate simulations is used to examine projected changes in the frequency, timing and spatial distribution of synthetic severe convective storm (SCS) detections based on peril proxies across three 15‐year epochs—1990–2005, 2040–2055 and 2085–2100—under intermediate and pessimistic emissions scenarios, including the first mid‐century projections of SCS activity,...
Pacific sardine (Sardinops sagax) are an economically important forage fish in the Northeast Pacific Ocean that undergo large changes in abundance over decadal scales and exhibit high individual variation in somatic growth. Past studies have suggested that somatic growth in Pacific sardine may be density-dependent and vary regionally in response to environmental conditions. We analyzed somatic growth in Pacific sardine off the...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Ecology of community reassembly: Movements and diets of megafauna during a decade of restoration in MozambiqueNARA Subscribed
The last decade has brought a worldwide surge of interest in rewilding—the repopulation of large herbivores and carnivores—as a strategy for conserving species and reviving ecosystem functions. Rewilding initiatives, if closely monitored, can provide unique insights into the ecology of the world's largest animals at otherwise impossible spatial and temporal scales. Capitalizing on these opportunities, and developing a knowledg...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Turnover in species composition often lags behind the pace of climate change, resulting in mismatches between climate and communities. However, the impact of these community‐climate disequilibria on ecosystem functions is rarely considered, and current methods for measuring disequilibria assume that species ranges were, until recently, in equilibrium with climate. Here, we develop a simple theoretical model to address both of...
Does acute stress induced via cold water immersion increase blood THC concentrations in regular cannabis users?NARA Subscribed
Rationale Δ 9 -tetrahydrocannabinol (THC), the principal intoxicant in cannabis, is a highly lipophilic substance that is readily stored in fat. Preclinical research suggests that fat-stored THC can be released into circulation under lipolytic conditions, such as stress. However, compelling evidence of this phenomenon is lacking in humans. Objectives Here, we investigated the effects of acute stress on blood (plasma) THC (and...