Gene-based therapies are being developed for retinal diseases, including RS1- related X-linked retinoschisis. Therefore it is essential to determine which variants are pathogenic and which are benign when enrolling patients. The Clinical Genome Resource (ClinGen) X-Linked Inherited Retinal Diseases (XLRD) Variant Curation Expert Panel (VCEP) brings together clinician scientists, molecular biologists, and geneticists to apply t...

Seaweeds are increasingly being incorporated into animal diets to address the challenge of intensifying food production while minimizing ecological impacts. Although seaweeds represent promising natural resources for developing economically and environmentally sustainable feeds, especially in aquaculture, the consequences of ingesting seaweed for the animals themselves are often unclear. Therefore, this study examined how the...

The Atlantic meridional overturning circulation (AMOC) is expected to decline dramatically over the 21st century, with severe impacts for Northern Hemisphere climate. After 20 years of sustained monitoring in the subtropics, a detectable AMOC weakening trend is now beginning to emerge. However, continuous observations at subpolar latitudes are currently too short-lived to determine any weakening signal above the large-amplitud...

Aim The temperature‐size rule is often described as a reduction in ectothermic asymptotic or maximum body size with warming. Although this coincides with the expectation that faster growth under warming would lead to larger sizes early in life but smaller sizes later in life, there remain few tests of changes in size across ontogeny. Here, we use > 99,000 observations of weight‐at‐age of commercially important fishes over 25 y...

An unprecedented marine heatwave in 2023 caused widespread coral bleaching and mortality throughout the Caribbean. In the Florida Keys (USA), 2 foundation species, elkhorn coral ( Acropora palmata ) and staghorn coral ( Acropora cervicornis ), were severely affected. These species have been the primary focus of reef restoration in Florida for decades. Substantial losses of these species occurred in outplanted populations, in o...

The Rockall Trough, northwest of Scotland and Ireland, is a key conduit for the North Atlantic Current (NAC) and European Slope Current (ESC) transporting heat and salt toward the Nordic Seas and Arctic Ocean while mediating exchanges between the open ocean and the European shelf. We present a decade-long record of Rockall Trough circulation from the Ellett Array providing the first continuous estimates of heat and freshwater...

Cardiac viral diseases are among the major causes of economic losses in Atlantic salmon ( Salmo salar L.) aquaculture. These include cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) and pancreas disease (PD) caused by Atlantic salmonid alphavirus (SAV). The resulting cardiomyopathies impact fish stock in terms of mortality, quality, growth performance and economic loss. Diagnosis of these diseases is cu...

With the increasing use of biodegradable plastics in agriculture and food packaging, it has become increasingly important to assess the effects of their fragmentation and mineralization in the environment (i.e., soil, compost). PBAT is a biodegradable polyester widely used in biodegradable mulch films that are intended to fragment and mineralize in soil. To study these effects, novel methodologies are needed to quantify PBAT m...