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Collection, handling and care of cephalopod eggsNARA Subscribed
Research on cephalopod early ontogeny has significantly advanced in recent decades, including embryo organogenesis and neurogenesis and early behavioural adaptations, particularly in commercially important and coastal species. Within this context, here we compiled current knowledge on the collection, handling and care under experimental conditions and monitoring in the field of cephalopod eggs and egg masses. It covers field o...
A novel splice site variant in DEGS1 leads to aberrant splicing and loss of DEGS1 enzyme activity, a VUS resolvedNARA Subscribed
Pathogenic DEGS1 variants have been reported in individuals with autosomal recessive hypomyelinating leukodystrophy 18 (HLD18; MIM# 618404). Here we describe three participants with HLD features and a previously unreported homozygous DEGS1 5′ splice site variant, c.825+4_825 + 5delAGinsTT (NM_003676.4). We used next-generation DNA and transcriptome sequencing, cell-based splicing assays, and tandem mass spectrometry to detect...
Genetic ancestry proportion influences risk of adverse events from tuberculosis treatment in BrazilNARA Subscribed
Tuberculosis (TB) treatment is highly effective, but response to therapy varies by geography and population subgroups. We assessed differences in TB treatment response in a representative and heterogeneous Brazilian population. We estimated genetic ancestry according to major genetic ancestry groups (African, European, and Amerindian) in the Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil cohort usi...
The impact of non-native trees on galling and herbivory in New York City across space and timeNARA Subscribed
Cities and suburbs frequently plant native and non-native trees as foundation species, with non-natives cultivated in these areas for centuries while remaining non-invasive. Although previous research has found that native trees often host more arthropods, studies have not simultaneously looked across space and time to determine the consistency of tree origin on urban arthropods. We combined varied methods across spatial and t...
Freshwater biodiversity in a rapidly changing Arctic: An expert horizon scan of key research questionsNARA Subscribed
Arctic freshwater biodiversity is rapidly changing due to climate warming, resource extraction, infrastructure development, and landscape transformation. To improve understanding, predict future responses, and inform policy formulation, research needs must be clearly identified. Using a horizon scan survey, Arctic freshwater experts from government, international agencies, and Indigenous Peoples identified 77 biodiversity rese...
Temperate Forest Floors: Ecosystem Hubs in Transition?NARA Subscribed
The forest floor (FF) plays a key role in carbon, nutrient, and water cycling. It is the biologically most active compartment of forest soils, highly responsive to environmental conditions. Yet, its response to current changes in environmental conditions and forest management is understudied. Temperate forests are among the best studied ecosystems globally, providing the necessary ecological and biogeochemical background infor...
Cognitive Outcomes Following Paediatric Mild Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Studies up to 2025NARA Subscribed
The purpose of this review was to provide a systematic and quantitative summary of recent literature relating to cognitive outcomes following paediatric mild traumatic brain injury (mTBI). Variable findings and diverse methodologies have thus far made it difficult to meaningfully integrate the extant literature. In this context, there is a need to examine the factors that define heterogeneity in this population and to critical...
The nonpeptide angiotensin-(1–7) mimic AVE0991 attenuates neuroendocrine and behavioral responses to chronic unpredictable stressNARA Subscribed
Rationale Chronic stress, frequently associated with dysfunction of the hypothalamic–pituitary–adrenal (HPA) axis and reduced neuroplasticity, is a major risk factor for psychiatric disorders such as anxiety and depression. Objective The present study aimed to validate a 21-day chronic unpredictable stress (CUS) model and to investigate the effects of the Mas receptor agonist AVE0991 on stress-induced behavioral and molecular...