Cain D. results 52
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This study explores the integration of black soldier fly larvae (BSFL) as a complementary functional ingredient to increase the soybean meal (SBM) inclusion in rainbow trout ( Oncorhynchus mykiss ) diets. Six experimental diets were formulated including a control diet as fishmeal (FM), an SBM‐based diet, and 2.5% and 5% whole‐body (WB) or defatted (DB) BSFL‐supplemented SBM‐based diets. Results revealed that BSFL inclusion pos...
Structural and genetic basis for the binding of a mouse monoclonal antibody to Flavobacterium psychrophilum lipopolysaccharideNARA Subscribed
A mouse monoclonal antibody (mAb FL100A) previously prepared against Flavobacterium psychrophilum ( Fp ) CSF259‐93 has now been examined for binding to lipopolysaccharides (LPS) of this strain and Fp 950106‐1/1. The corresponding O‐polysaccharides (O‐PS) of these strains are formed by identical trisaccharide repeats composed of l ‐Rhamnose ( l ‐Rha), 2‐acetamido‐2‐deoxy‐ l ‐fucose ( l ‐FucNAc) and 2‐acetamido‐4‐R 1 ‐2,4‐dideox...
Heat stress can increase disease risk in fishes by reducing immune function. Interactions between redband trout ( Oncorhynchus mykiss gairdneri ) and Flavobacterium columnare , a causative agent of columnaris disease, provide an opportunity to investigate the effects of temperature on immune function and disease resistance during periods of thermal stress. We conducted three trials to characterise differences in immune functio...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Iron is essential for growth and virulence in most pathogenic bacterial strains. In some cases, the hosts for these pathogenic bacteria develop specialized strategies to sequester iron and limit infectivity. This in turn may result in the invading pathogens utilizing high‐affinity iron transport mechanisms, such as the use of iron‐chelating siderophores, to extend beyond the host defences. Flavobacterium psychrophilum , the ca...
Salmonid diseases caused by infections of Flavobacterium psychrophilum , the causative agent of bacterial coldwater disease, remain difficult to manage as novel, pathogenic strains continue to emerge in aquaculture settings globally. To date, much of the research regarding treatment options and vaccine development has focused on rainbow trout ( Oncorhynchus mykiss ), but other inland‐reared salmonids are also impacted by this...
For salmonid producers, a common threat is Flavobacterium psychrophilum . Recent advancements in bacterial coldwater disease (BCWD) management include the development of a live‐attenuated immersion vaccine that cross‐protects against an array of F. psychrophilum strains. Emerging family Flavobacteriaceae cases associated with clinical disease have been increasing, including pathogenic isolates of Flavobacterium spp. and Chryse...
Isolation and experimental challenge of cultured burbot ( Lota lota maculosa ) with Flavobacterium columnare and Aeromonas sp. isolatesNARA Subscribed
Burbot ( Lota lota maculosa ) are a potential new species for commercial aquaculture. As burbot culture expands, there is a need to further define pathogen susceptibility and characterize aspects of the burbot immune response in an effort to assess fish health. A recent clinical diagnostic case from juvenile burbot reared at a commercial production facility resulted in the isolation and identification of Flavobacterium columna...
Co‐infection of rainbow trout ( Oncorhynchus mykiss ) with infectious hematopoietic necrosis virus and Flavobacterium psychrophilumNARA Subscribed
Co‐infection of rainbow trout with infections haematopoietic necrosis virus (IHNV) and Flavobacterium psychrophilum is known to occur, and it has been speculated that a combined infection can result in dramatic losses. Both pathogens can persist in fish in an asymptomatic carrier state, but the impact of co‐infection has not been well characterized or documented. In this study, it was hypothesized that fish co‐infected with F....
Front CoverNARA Subscribed
Bacterial coldwater disease, caused by Flavobacterium psychrophilum , remains one of the most significant bacterial diseases of salmonids worldwide. A previously developed and reported live‐attenuated immersion vaccine ( F. psychrophilum ; B.17‐ ILM ) has been shown to confer significant protection to salmonids. To further characterize this vaccine, a series of experiments were carried out to determine the cross‐protective eff...
Flavobacterium psychrophilum is the causative agent of bacterial coldwater disease ( BCWD ), which has a major impact on salmonid aquaculture globally. An Enterobacter species, C6‐6, isolated from the gut of rainbow trout, Oncorhynchus mykiss (Walbaum), has been identified as a potential probiotic species providing protection against BCWD . This study examined the effects of alginate microencapsulation on the protective effica...