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SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Experimental constraints on shallow differentiation of high-Mg andesite at Whakaari, New ZealandNARA Subscribed
Phase equilibrium experiments were used to determine conditions of melt evolution and phenocryst growth in high-Mg andesite magmas that were erupted at Whakaari (White Island) in New Zealand between 1976 and 2000. The high-Mg andesites are both mafic (7.21–10.3 wt% MgO) and silica-rich (55.3–58.6 wt% SiO 2 ) with phenocrysts of plagioclase, orthopyroxene, clinopyroxene, olivine, Cr-spinel and Fe–Ti oxides contained in a glassy...
Model-informed Drug Development (MIDD) Approach to Support Biopharmaceutical Development of IberdomideNARA Subscribed
Iberdomide is a BCS III CELMoD™ agent currently under development for treatment of multiple myeloma. Five formulations were used during clinical development, starting with active ingredient in gelatin capsule (AIC), followed by subsequent formulations in gelatin (F1), HPMC capsules (F2 and F3), and finally the intended commercial form (ICF). A food effect study with the Phase I AIC formulation showed no food effect and two rel...
Homologous recombination between bacterial strains is theoretically capable of preventing the separation of daughter clusters, and producing cohesive clouds of genotypes in sequence space. However, numerous barriers to recombination are known. Barriers may be essential such as adaptive incompatibility, or ecological, which is associated with the opportunities for recombination in the natural habitat. Campylobacter jejuni is a...
Phenotypic divergence during the invasion of Phyla canescens in Australia and France: evidence for selection‐driven evolutionNARA Subscribed
Rapid adaptive evolution has been advocated as a mechanism that promotes invasion. Demonstrating adaptive evolution in invasive species requires rigorous analysis of phenotypic shifts driven by selection. Here, we document selection‐driven evolution of Phyla canescens , an Argentine weed, in two invaded regions (Australia and France). Invasive populations possessed similar or higher diversity than native populations, and displ...
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