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European badgers ( Meles meles ) play an important role in the epidemiology of bovine tuberculosis (caused by Mycobacterium bovis ) in England, but little is known about the prevalence of atypical mycobacteriosis. Badgers are also known to be infected by other infectious agents, and the relationship between mycobacteriosis and concomitant infections needs further investigation. Overall, 88 badger carcasses from the Midlands of...
Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learningNARA Subscribed
The in vitro micronucleus assay is a globally significant method for DNA damage quantification used for regulatory compound safety testing in addition to inter-individual monitoring of environmental, lifestyle and occupational factors. However, it relies on time-consuming and user-subjective manual scoring. Here we show that imaging flow cytometry and deep learning image classification represents a capable platform for automat...
To respect the Paris agreement targeting a limitation of global warming below 2°C by 2100, and possibly below 1.5°C, drastic reductions of greenhouse gas emissions are mandatory but not sufficient. Large‐scale deployment of other climate mitigation strategies is also necessary. Among these, increasing soil organic carbon (SOC) stocks is an important lever because carbon in soils can be stored for long periods and land manageme...
Differential permeability of rivers to raccoon gene flow corresponds to rabies incidence in Ontario, CanadaNARA Subscribed
The correlation of landscape features with genetic discontinuities reveals barriers to dispersal that can contribute to understanding present and future spread of wildlife diseases. This knowledge can then be used for targeting control efforts. The impact of natural barriers on raccoon dispersal was assessed through genetic analysis of samples from two regions, Niagara ( N = 666) and St. Lawrence ( N = 802). These areas are tr...
Poster abstractsNARA Subscribed
Does the Lack of Reference Ecosystems Limit Our Science? A Case Study in Nonnnative Invasive Plants as Forest FuelsNARA Subscribed
In forest experiments the problem of inadequate controls often arises. True controls might not be required in case studies, comparisons along an environmental gradient, or comparisons of multiple treated and untreated areas. In a recent characterization of fuels in invaded and uninvaded forest conditions for four forest types at 12 locations in Maine, Maryland, Massachusetts, New Jersey, New York, Vermont, and Virginia, high-q...
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