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Jellyfish, often primarily perceived by the public as a marine nuisance, represent an increasingly valuable and sustainable source of diverse biomolecules with significant potential for the biomedical sciences, in addition to their crucial ecological role within marine ecosystems. This review explores the properties, extraction and applications of key jellyfish-derived compounds, including collagen, peptides, sulfated polysacc...
Rebalancing Immune Interactions within the Brain-Spleen Axis Mitigates Neuroinflammation in an Aging Mouse Model of Alzheimer’s DiseaseNARA Subscribed
Alzheimer’s disease (AD) is the most common cause of dementia worldwide, characterized by accumulation of amyloid-β protein and hyperphosphorylated tau protein in the brain. Neuroinflammation, resulting from chronic activation of brain-resident innate immune cells as well as enhanced peripheral leukocyte access across the blood–brain barrier, crucially affects AD progression. In this context, TNFSF10, a cytokine substantially...
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