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The oceanic mixed layer in the Southern Ocean is characterized by numerous fronts due to the stirring of freshwater influxes arising from ice melting. The interaction of these fronts with winds modulates the evolution of the mixed layer and affects atmosphere–ocean energy exchanges. However, the underlying mechanism behind the wind-front interaction remains obscure due to a lack of three-dimensional observations of the ocean,...
Collar structures are widely used to protect monopile foundations from scour, but their geometric obstruction hinders direct observation of the surrounding flow in physical experiments. To overcome this limitation, this study employs large-eddy simulation (LES) to investigate the flow characteristics around a monopile with collar protection. The LES model was validated against well-documented experimental data of pile-induced...
FSD1 inhibits glioblastoma diffuse infiltration through restriction of HDAC6-mediated microtubule deacetylationNARA Subscribed
The infiltration of glioblastoma multiforme (GBM) is predominantly characterized by diffuse spread, contributing significantly to therapy resistance and recurrence of GBM. In this study, we reveal that microtubule deacetylation, mediated through the downregulation of fibronectin type III and SPRY domain-containing 1 (FSD1), plays a pivotal role in promoting GBM diffuse infiltration. FSD1 directly interacts with histone deacety...
Quantifying the dynamical and radiative processes of the drastically weak South Asian summer monsoon circulation in 2015NARA Subscribed
The South Asian summer monsoon (SASM) circulation in 2015 is the weakest since 2000s, which results in severe drought over broad regions of the Indian peninsula. The 2015 SASM is closely related to the weakened summer meridional thermal contrast between southern Eurasia (SE) and the tropical Indian Ocean (TIO) at the mid–upper troposphere. Based on an updated climate feedback-response analysis method, this study conducts a qua...
Upwelling is a widespread phenomenon in the ocean and plays key roles in the marine environment, marine fishery and air–sea carbon exchange. In coastal regions, the upwelling is usually modulated by tides and complex topography, but the dynamical mechanism is still unclear and yet to be quantified. In this study, a three-dimensional (3D) regional ocean model is used to investigate tide-induced upwelling and its mechanisms quan...
A multi-model prediction system for ENSONARA Subscribed
Mesoscale eddies propagate westward in the northwestern Pacific Ocean and interact with the Kuroshio in the vicinity of the western boundary of the ocean. However, the processes affecting the eddy properties and the detailed structure of the eddies when they encounter the Kuroshio remain unclear. In this study, we analyze the statistics of the eddy properties around the Kuroshio using 25 years of satellite altimeter data and t...