The wingless-related integration site (Wnt) signaling pathway plays an essential role in embryonic development and nervous system regulation. It is critically involved in multiple types of neuropathic pain (NP), such as HIV-related NP, cancer pain, diabetic neuralgia, multiple sclerosis-related NP, endometriosis pain, and other painful diseases. Wnt signaling is also implicated in the pain induced by sciatic nerve compression...

Epidermal stem cells (ESCs) are critical for skin regeneration and repair. Previous studies have shown that ESCs are susceptible to oxidative stress, which in turn leads to lipid peroxidation and affects skin repair. Our study aims to explore how ESCs resist lipid peroxidation. By performing proteomics analysis, we found that the expression of Acyl-CoA thioesterase 7 (ACOT7) was positively correlated with the concentration of...

Trophic research is essential to the conservation and management of fishery resources. This study analyzed the feeding habits and nutritional interactions among three tuna species in the waters of the Solomon Islands (5°12′S–15°20′S, 157°31′E–172°19′E). A total of 103 bigeye tuna ( Thunnus obesus ), 296 yellowfin tuna ( Thunnus albacores ), and 264 albacore tuna ( Thunnus alalunga ) samples were collected from September to Dec...

To study the effect of Ca/P ratio on the P and Ca absorption and excretion in hybrid sturgeon (Huso dauricus♀ X Acipenser schrenckii♂), five groups of fish were intubated with 100 mg P·kg−1 BW with the Ca/P ratios of 0:1, 0.25:1, 0.5:1, 1:1, and 2:1. Plasma P concentrations were significantly elevated at Ca/P ratios below 2:1, and the highest value was obtained at Ca/P ratio of 0.5:1. Plasma Ca content was significantly increa...

Mass stock enhancement and release are excellent ways to recover Coilia nasus resources. However, it is challenging to evaluate stock enhancement effectively, and it is important to establish a method suitable for estimating C. nasus populations. We explored the effectiveness of marking otoliths in these fish with strontium by immersing C. nasus in hexahydrate strontium chloride solutions. We used laser ablation inductively co...

In order to scientifically and reasonably evaluate the safety risk of ship navigation, to and better solve the problems of the poor sensitivity of static evaluation and insufficient ability to grasp the overall dynamic situation, in this paper, representative safety evaluation indexes for ship navigation are screened and the initial weight of each index is confirmed in combination with the improved analytic hierarchy process (...

Genetic manipulation of Haematococcus pluvialis is difficult because of the lack of a stable and convenient transformation system. The pH124-EGFP-Ble vector containing ble as a selective gene and EGFP as a reporter gene was constructed and employed for effective transformation. H. pluvialis protoplasts were obtained by treating with cellulase and macerozeme. Then polyethylene glycol-mediated transformation was established by i...