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Colony-stimulating factor 1 receptor (CSF1R) inhibitors, such as PLX5622 and PLX3397 (pexidartinib), are widely used for in vivo microglial depletion and for investigating microglial functions and therapeutic potential. Although CSF1R inhibitor-based studies have uncovered important roles for microglia in processes, such as anesthesia, addiction, and obesity, whether the resulting phenotypes reflect microglial depletion alone...
Precision measurement of the Ds*+-Ds+ meson mass differenceNARA Subscribed
Divergent Mechanisms Drive Multi‐Decadal Drought Intensification in South America: A Trend Turning Analysis From 1958 to 2023NARA Subscribed
South America is undergoing an unprecedented drought crisis, threatening water security, ecosystem integrity and socioeconomic stability. While individual extreme drought events are well documented, the temporal evolution and mechanistic drivers of long‐term drought intensification remain poorly understood. Here, we employ the Running Slope Difference (RSD)– t ‐test method to analyse Palmer Drought Severity Index (PDSI) and so...