Coastal freak waves (CFWs) are sudden and hazardous wave events that occur near shorelines and can pose serious threats to coastal visitors and infrastructure. Due to the complex interactions among coastal bathymetry, wave dynamics, and environmental conditions, the mechanisms governing CFW formation remain poorly understood, making reliable prediction difficult. This study investigates the feasibility of applying machine lear...

Major depressive disorder (MDD) is a major public health issue worldwide. It not only causes an increased socio-economic burden, but also negatively affects personal lives. It has been shown that depression leads to impairments in synaptic plasticity, such as impaired long-term potentiation (LTP) in the prefrontal cortex (PFC). A recent study reported that administration of agomelatine, a melatonin receptor agonist and 5-hydro...