Moyamoya disease (MMD) is a cerebrovascular disorder marked by progressive arterial narrowing, categorized into six stages known as Suzuki stages based on angiographic features. Growing evidence indicates a pivotal role of systemic immune and inflammatory responses in the initiation and advancement of MMD. This study employs high-dimensional mass cytometry to reveal the immunophenotypic characteristics of peripheral blood immu...

As the northernmost locality yielding one of the most representative Early Pleistocene Gigantopithecus – Sinomastodon faunas in southern China, the Longgupo site has preserved valuable geological archives that have significantly improved our understanding of Pleistocene biostratigraphy and biogeography. A convincing chronological framework of this locality is therefore important to elaborate on the evolution of Quaternary faun...