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Microneedles have emerged as a promising technology for enhancing transdermal delivery. The micron-sized needles penetrate the stratum corneum with minimal pain and discomfort. Among the different microneedle types, hydrogel microneedles offer distinct advantages, including sustained drug release and biocompatibility. The present study aimed to optimize the formulation of hydrogel microneedles composed of Gantrez ® S-97, a hyd...