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The Fukushima Daiichi Nuclear Power Plant accident released radionuclides directly into the ocean as a result of the Great East Japan Earthquake on March 11, 2011. This material has been transported across the Pacific Ocean and detected in the northeastern Pacific. We began a surface ocean 129 I monitoring program a few months after this disaster in June 2011, with samples from Scripps Pier, La Jolla, California, USA, with the...
STAT3 Signaling Mediates Agomelatine Restoration of Prefrontal Cortex Synaptic Plasticity in Chronic Social Defeat Stress MiceNARA Subscribed
Major depressive disorder (MDD) is a major public health issue worldwide. It not only causes an increased socio-economic burden, but also negatively affects personal lives. It has been shown that depression leads to impairments in synaptic plasticity, such as impaired long-term potentiation (LTP) in the prefrontal cortex (PFC). A recent study reported that administration of agomelatine, a melatonin receptor agonist and 5-hydro...
This study presents an optimized system for ship route planning. Computational fluid dynamics simulations were used to modify Kwon’s semi-empirical speed loss estimation method, enabling efficient route planning under variable sea conditions. The study focused on improving the prediction of speed loss in irregular waves for container ships and further applying this to ship-optimized voyage planning. Dynamic programming was use...