Bacteria of the Streptomyces genus colonize diverse ecological niches and can exhibit diverse traits of potential applied value. With regards to crop production, some species can induce plant diseases while others are capable of promoting plant growth or controlling diseases. To identify Taiwanese Streptomyces strains suitable for crop growth promotion and disease management, this study obtained 49 potato-isolated, Streptomyce...

Autism spectrum disorder (ASD), a neurodevelopmental disorder, is characterized by synaptic dysregulation as its underlying pathophysiological mechanism. AMP-activated protein kinase (AMPK), an intracellular energy sensor, plays a pivotal role in regulating synaptic integrity and function. Current treatments for ASD exhibit limited benefits in alleviating the core symptoms of ASD. Consequently, we investigated the therapeutic...

Hemodynamic parameters derived from pulse wave analysis have been shown to predict long-term outcomes in patients with heart failure (HF). Here we aimed to develop a deep-learning based algorithm that incorporates pressure waveforms for the identification and risk stratification of patients with HF. The first study, with a case–control study design to address data imbalance issue, included 431 subjects with HF exhibiting typic...