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Change in mitochondrial capacity in elite triathletes, cyclists, and wrestlers over a training period of 28 daysNARA Subscribed
Purpose This study investigated the change in mitochondrial capacity and V O 2 max in elite triathlon, cycling, and Greco-Roman wrestling athletes over a 28-day training period. Methods Sixteen elite athletes (23 ± 2.5 years; 176 ± 6 cm; 76 ± 8 kg; 65 ± 6.9 ml/min/kg) participated. Mitochondrial capacity was assessed before (pre) and after (post) a 28-day training period by measuring the increase in deoxygenated hemoglobin (HH...
Ocean acidification (OA) generally receives far less consideration than other climate stressors and related hazards, such as global warming and extreme weather events. Canada is uniquely vulnerable to OA given its extensive coastal oceans, the oceanographic processes in its three basins, accelerated warming and sea-ice melt, and extensive coastal communities and maritime economic sectors. Canada’s coastline is also home to ext...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
The Cost of Antivenom: A Cost Minimization Study using the North American Snakebite RegistryNARA Subscribed
Envenomation is a global health issue, with over 9,000 encounters managed in the United States yearly. The introduction of immunoglobulin fragment antivenom has reduced the risk of hypersensitivity. This study compares treatment costs of crotaline envenomation using the Fab and F(ab’) 2 antivenoms as reported to the North American Snakebite Registry (NASBR), a nationwide surveillance tool. Methods This was a retrospective anal...
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed
Estimating kill intervals for a specific prey species using location clusters from GPS-collared Eurasian lynx (Lynx lynx)NARA Subscribed
An increasing number of GPS telemetry studies have helped to gain important insights into predator-prey relationships in recent years. However, considerable time and effort is needed to evaluate whether GPS location clusters (GLCs) reflect predation events. To reduce field effort, predictive models are being developed to calculate predator kill intervals, but few studies have attempted to do this for a specific species of prey...
Effects of muscle fatigue on exercise-induced hamstring muscle damage: a three-armed randomized controlled trialNARA Subscribed
Purpose Hamstring injuries in soccer reportedly increase towards the end of the matches’ halves as well as with increased match frequency in combination with short rest periods, possibly due to acute or residual fatigue. Therefore, this study aimed to investigate the effects of acute and residual muscle fatigue on exercise-induced hamstring muscle damage. Methods A three-armed randomized-controlled trial, including 24 resistan...
The Toxicology Investigators Consortium 2022 Annual ReportNARA Subscribed
Low circulating adropin concentrations predict increased risk of cognitive decline in community-dwelling older adultsNARA Subscribed
The secreted peptide adropin is highly expressed in human brain tissues and correlates with RNA and proteomic risk indicators for dementia. Here we report that plasma adropin concentrations predict risk for cognitive decline in the Multidomain Alzheimer Preventive Trial (ClinicalTrials.gov Identifier, NCT00672685; mean age 75.8y, SD = 4.5 years, 60.2% female, n = 452). Cognitive ability was evaluated using a composite cognitiv...
The Toxicology Investigators Consortium 2020 Annual ReportNARA Subscribed
High summer temperatures amplify functional differences between coral‐ and algae‐dominated reef communitiesNARA Subscribed
Shifts from coral to algal dominance are expected to increase in tropical coral reefs as a result of anthropogenic disturbances. The consequences for key ecosystem functions such as primary productivity, calcification, and nutrient recycling are poorly understood, particularly under changing environmental conditions. We used a novel in situ incubation approach to compare functions of coral‐ and algae‐dominated communities in t...