Immunophenotyping of tumor-infiltrating immune cells is increasingly important for understanding the tumor microenvironment (TME), particularly in the diagnosis and treatment of skin cancer. CD1a + dendritic cells (DC) initiate T cell activation by presenting tumor antigens, while T cells directly target tumor cells. Analyzing their spatial distribution in different types of skin cancer can provide insights into immune respons...

For decades, the honeybee, Apis mellifera , has suffered from severe colony losses due to the ectoparasitic mite Varroa destructor . Various strategies based on chemicals fail to adequately control varroa mite populations, and often comprise side-effects on the host, parasite resistance and residues in hive products. Reduced temperature tolerance of V. destructor compared to its host has long been recognised and accordingly, t...