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Regulation of PDGF-BB signaling in placental pericytes by soluble PDGFRβ isoforms: implications for fetoplacental vascular developmentNARA Subscribed
Vascular remodeling within the developing fetus and placenta is essential for supporting the growth and function of emerging tissues and organs. Pericytes (PCs) play a central role in stabilizing and maturing microvascular networks by extending along endothelial cells (ECs) and reinforcing vessel integrity. In the placenta, as in other organs, PC–EC communication is mediated in part by platelet-derived growth factor-BB (PDGF‑B...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
The Cost of Antivenom: A Cost Minimization Study using the North American Snakebite RegistryNARA Subscribed
Envenomation is a global health issue, with over 9,000 encounters managed in the United States yearly. The introduction of immunoglobulin fragment antivenom has reduced the risk of hypersensitivity. This study compares treatment costs of crotaline envenomation using the Fab and F(ab’) 2 antivenoms as reported to the North American Snakebite Registry (NASBR), a nationwide surveillance tool. Methods This was a retrospective anal...
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed
The field of oceanography is transitioning from data-poor to data-rich, thanks in part to increased deployment of in-situ platforms and sensors, such as those that instrument the US-funded Ocean Observatories Initiative (OOI). However, generating science-ready data products from these sensors, particularly those making biogeochemical measurements, often requires extensive end-user calibration and validation procedures, which c...
Restoration ecology through the lens of coexistence theoryNARA Subscribed
The Toxicology Investigators Consortium 2022 Annual ReportNARA Subscribed
Linking changes in species composition and biomass in a globally distributed grassland experimentNARA Subscribed
Global change drivers, such as anthropogenic nutrient inputs, are increasing globally. Nutrient deposition simultaneously alters plant biodiversity, species composition and ecosystem processes like aboveground biomass production. These changes are underpinned by species extinction, colonisation and shifting relative abundance. Here, we use the Price equation to quantify and link the contributions of species that are lost, gain...
Hypoxia and HematopoiesisNARA Subscribed
Motivation The BioTIME database contains raw data on species identities and abundances in ecological assemblages through time. These data enable users to calculate temporal trends in biodiversity within and amongst assemblages using a broad range of metrics. BioTIME is being developed as a community‐led open‐source database of biodiversity time series. Our goal is to accelerate and facilitate quantitative analysis of temporal...
Detection and differentiation of V ibrio vulnificus and V . sinaloensis in water and oysters of a G ulf of M exico estuaryNARA Subscribed
Summary V ibrio vulnificus is a potentially lethal human pathogen that occurs naturally in estuarine waters and shellfish. V ibrio vulnificus was quantified in water and oysters from F lorida's G ulf C oast by plating on mCPC agar, enrichment and plating, and quantitative PCR ( qPCR ). V ibrio vulnificus was detected in 19%, 29%, and 97% of samples respectively by direct plating, qPCR , and enrichment. Only 8% of typical colon...
Clear‐sky, upwelling shortwave flux at the top of the atmosphere $\left(S_{\rm {TOA}}^{\uparrow}\right)$ , simulated using the atmospheric and land model components of the Community Climate System Model 3 (CCSM3), is compared to corresponding observational estimates from the Clouds and Earth's Radiant Energy System (CERES) sensor. Improvements resulting from the use of land surface albedo derived from Moderate Resolution Imagi...
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