Christopher J. Hewitt - NARA Discovery

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An evaluation of the performance of a scroll machine in a reversible high-temperature heat pump - organic Rankine cycle system using R1233zd(E) as the working fluidNARA Subscribed

International Journal of Refrigeration · 2025 · Vol. 174 · Elsevier

Rahul Velanparambil Ravindran; Donal Cotter; Christopher Wilson; Ming Jun Huang; Neil J Hewitt

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Isopropyl alcohol inhalation versus 5-HT3 antagonists for treatment of nausea: a meta-analysis of randomised controlled trialsNARA Subscribed

European Journal of Clinical Pharmacology · 2023 · Vol. 79 · Issue 11 · Springer

James S. Kimber; Joshua G. Kovoor; John M. Glynatsis; Samuel J. West; Thi Thien Nhi Mai; Jonathan Henry W. Jacobsen; Christopher D. Ovenden; Stephen Bacchi; Joseph N. Hewitt; Aashray K. Gupta; Suzanne Edwards; Fiona J. Taverner; David I. Watson

Purpose Nausea is a common and unpleasant sensation for which current therapies such as serotonin (5-HT 3 ) antagonists are often ineffective, while also conferring a risk of potential adverse events. Isopropyl alcohol (IPA) has been proposed as a treatment for nausea. We aimed to compare IPA with 5-HT 3 antagonists for the treatment of nausea across all clinical settings. Methods MEDLINE, EMBASE, PubMed, CENTRAL and CINAHL we...

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Design and development of a new ambr250® bioreactor vessel for improved cell and gene therapy applicationsNARA Subscribed

Biotechnology Letters · 2021 · Vol. 43 · Issue 5 · Springer

Marco Rotondi; Ned Grace; John Betts; Neil Bargh; Elena Costariol; Barney Zoro; Christopher J. Hewitt; Alvin W. Nienow; Qasim A. Rafiq

The emergence of cell and gene therapies has generated significant interest in their clinical and commercial potential. However, these therapies are prohibitively expensive to manufacture and can require extensive time for development due to our limited process knowledge and understanding. The automated ambr250® stirred-tank bioreactor platform provides an effective platform for high-throughput process development. However, th...

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Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortiumNARA Subscribed

Human Genetics · 2015 · Vol. 134 · Issue 2 · Springer

Qing Li; Robert Wojciechowski; Claire L. Simpson; Pirro G. Hysi; Virginie J. M. Verhoeven; Mohammad Kamran Ikram; René Höhn; Veronique Vitart; Alex W. Hewitt; Konrad Oexle; Kari-Matti Mäkelä; Stuart MacGregor; Mario Pirastu; Qiao Fan; Ching-Yu Cheng; Beaté St Pourcain; George McMahon; John P. Kemp; Kate Northstone; Jugnoo S. Rahi; Phillippa M. Cumberland; Nicholas G. Martin; Paul G. Sanfilippo; Yi Lu; Ya Xing Wang; Caroline Hayward; Ozren Polašek; Harry Campbell; Goran Bencic; Alan F. Wright; Juho Wedenoja; Tanja Zeller; Arne Schillert; Alireza Mirshahi; Karl Lackner; Shea Ping Yip; Maurice K. H. Yap; Janina S. Ried; Christian Gieger; Federico Murgia; James F. Wilson; Brian Fleck; Seyhan Yazar; Johannes R. Vingerling; Albert Hofman; André Uitterlinden; Fernando Rivadeneira; Najaf Amin; Lennart Karssen; Ben A. Oostra; Xin Zhou; Yik-Ying Teo; E. Shyong Tai; Eranga Vithana; Veluchamy Barathi; Yingfeng Zheng; Rosalynn Grace Siantar; Kumari Neelam; Youchan Shin; Janice Lam; Ekaterina Yonova-Doing; Cristina Venturini; S. Mohsen Hosseini; Hoi-Suen Wong; Terho Lehtimäki; Mika Kähönen; Olli Raitakari; Nicholas J. Timpson; David M. Evans; Chiea-Chuen Khor; Tin Aung; Terri L. Young; Paul Mitchell; Barbara Klein; Cornelia M. van Duijn; Thomas Meitinger; Jost B. Jonas; Paul N. Baird; David A. Mackey; Tien Yin Wong; Seang-Mei Saw; Olavi Pärssinen; Dwight Stambolian; Christopher J. Hammond; Caroline C. W. Klaver; Cathy Williams; Andrew D. Paterson; Joan E. Bailey-Wilson; Jeremy A. Guggenheim

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Multiparameter flow cytometry for the characterisation of extracellular markers on human mesenchymal stem cellsNARA Subscribed

Biotechnology Letters · 2014 · Vol. 36 · Issue 4 · Springer

Alexander K. C. Chan; Thomas R. J. Heathman; Karen Coopman; Christopher J. Hewitt

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Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactorNARA Subscribed

Biotechnology Letters · 2013 · Vol. 35 · Issue 8 · Springer

Qasim A. Rafiq; Kathryn M. Brosnan; Karen Coopman; Alvin W. Nienow; Christopher J. Hewitt

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Multiparameter flow cytometry for the characterization of human embryonic stem cellsNARA Subscribed

Biotechnology Letters · 2013 · Vol. 35 · Issue 1 · Springer

Kathryn Brosnan; Andrew Want; Karen Coopman; Christopher J. Hewitt

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Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortiumNARA Subscribed

Human Genetics · 2012 · Vol. 131 · Issue 9 · Springer

Virginie J. M. Verhoeven; Pirro G. Hysi; Seang-Mei Saw; Veronique Vitart; Alireza Mirshahi; Jeremy A. Guggenheim; Mary Frances Cotch; Kenji Yamashiro; Paul N. Baird; David A. Mackey; Robert Wojciechowski; M. Kamran Ikram; Alex W. Hewitt; Priya Duggal; Sarayut Janmahasatian; Chiea-Chuen Khor; Qiao Fan; Xin Zhou; Terri L. Young; E-Shyong Tai; Liang-Kee Goh; Yi-Ju Li; Tin Aung; Eranga Vithana; Yik-Ying Teo; Wanting Tay; Xueling Sim; Igor Rudan; Caroline Hayward; Alan F. Wright; Ozren Polasek; Harry Campbell; James F. Wilson; Brian W. Fleck; Isao Nakata; Nagahisa Yoshimura; Ryo Yamada; Fumihiko Matsuda; Kyoko Ohno-Matsui; Abhishek Nag; George McMahon; Beate St. Pourcain; Yi Lu; Jugnoo S. Rahi; Phillippa M. Cumberland; Shomi Bhattacharya; Claire L. Simpson; Larry D. Atwood; Xiaohui Li; Leslie J. Raffel; Federico Murgia; Laura Portas; Dominiek D. G. Despriet; Leonieke M. E. van Koolwijk; Christian Wolfram; Karl J. Lackner; Anke Tönjes; Reedik Mägi; Terho Lehtimäki; Mika Kähönen; Tõnu Esko; Andres Metspalu; Taina Rantanen; Olavi Pärssinen; Barbara E. Klein; Thomas Meitinger; Timothy D. Spector; Ben A. Oostra; Albert V. Smith; Paulus T. V. M. de Jong; Albert Hofman; Najaf Amin; Lennart C. Karssen; Fernando Rivadeneira; Johannes R. Vingerling; Guðný Eiríksdóttir; Vilmundur Gudnason; Angela Döring; Thomas Bettecken; André G. Uitterlinden; Cathy Williams; Tanja Zeller; Raphaële Castagné; Konrad Oexle; Cornelia M. van Duijn; Sudha K. Iyengar; Paul Mitchell; Jie Jin Wang; René Höhn; Norbert Pfeiffer; Joan E. Bailey-Wilson; Dwight Stambolian; Tien-Yin Wong; Christopher J. Hammond; Caroline C. W. Klaver

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Expansion of human mesenchymal stem cells on microcarriersNARA Subscribed

Biotechnology Letters · 2011 · Vol. 33 · Issue 11 · Springer

Christopher J. Hewitt; Ken Lee; Alvin W. Nienow; Robert J. Thomas; Mark Smith; Colin R. Thomas

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Multi-parameter flow cytometry and cell sorting reveal extensive physiological heterogeneity in Bacillus cereus batch culturesNARA Subscribed

Biotechnology Letters · 2011 · Vol. 33 · Issue 7 · Springer

Andrew Want; Helen Hancocks; Colin R. Thomas; Stuart M. Stocks; Gerhard Nebe-von-Caron; Christopher J. Hewitt

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An investigation into the preservation of microbial cell banks for α-amylase production during 5 l fed-batch Bacillus licheniformis fermentationsNARA Subscribed

Biotechnology Letters · 2010 · Vol. 32 · Issue 10 · Springer

Nichola H. Hancocks; Colin R. Thomas; Stuart M. Stocks; Christopher J. Hewitt

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Studies supporting the use of mechanical mixing in large scale beer fermentationsNARA Subscribed

Biotechnology Letters · 2010 · Vol. 32 · Issue 5 · Springer

Alvin W. Nienow; Georgina McLeod; Christopher J. Hewitt

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Induction studies with Escherichia coli expressing recombinant interleukin-13 using multi-parameter flow cytometryNARA Subscribed

Biotechnology Letters · 2009 · Vol. 31 · Issue 4 · Springer

Jennifer O. Shitu; John M. Woodley; Richard Wnek; Michel Chartrain; Christopher J. Hewitt

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Dystroglycan glycosylation and muscular dystrophyNARA Subscribed

Glycoconjugate Journal · 2009 · Vol. 26 · Issue 3 · Springer

Christopher J. Moore; Jane E. Hewitt

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Polyhydroxybutyrate accumulation by a Serratia sp.NARA Subscribed

Biotechnology Letters · 2008 · Vol. 30 · Issue 3 · Springer

Harriet Lugg; Rachel L. Sammons; Peter M. Marquis; Christopher J. Hewitt; Ping Yong; Marion Paterson-Beedle; Mark D. Redwood; Artemis Stamboulis; Mitra Kashani; Mike Jenkins; Lynne E. Macaskie

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The Use of Phase Inversion Temperature (PIT) Microemulsion Technology to Enhance Oil Utilisation during Streptomyces rimosus Fed-batch Fermentations to Produce OxytetracyclineNARA Subscribed

Biotechnology Letters · 2005 · Vol. 27 · Issue 20 · Springer

Panos A. Papapanagiotou; Henry Quinn; Jean-Pierre Molitor; Alvin W. Nienow; Christopher J. Hewitt

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Laboratory Scale Bioremediation of Acid Mine Water Drainage from a Disused Tin MineNARA Subscribed

Biotechnology Letters · 2005 · Vol. 27 · Issue 17 · Springer

Lawrence Darkwah; Neil A. Rowson; Christopher J. Hewitt

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Monitoring and quantification of inclusion body formation in Escherichia coli by multi-parameter flow cytometryNARA Subscribed

Biotechnology Letters · 2005 · Vol. 27 · Issue 13 · Springer

Fredrik Wållberg; Helene Sundström; Erika Ledung; Christopher J. Hewitt; Sven-Olof Enfors

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The impact of fluid mechanical stress on Corynebacterium glutamicum during continuous cultivation in an agitated bioreactorNARA Subscribed

Biotechnology Letters · 2005 · Vol. 27 · Issue 10 · Springer

Saethawat Chamsartra; Christopher J. Hewitt; Alvin W. Nienow

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Segregation to non-dividing cells in recombinant Escherichia coli fed-batch fermentation processesNARA Subscribed

Biotechnology Letters · 2004 · Vol. 26 · Issue 19 · Springer

Heléne Sundström; Fredrik Wållberg; Erika Ledung; Bo Norrman; Christopher J. Hewitt; Sven-Olof Enfors

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A study into the anti-microbial properties of an amino functionalised polymer using multi-parameter flow cytometryNARA Subscribed

Biotechnology Letters · 2004 · Vol. 26 · Issue 7 · Springer

Christopher J. Hewitt; Robert Franke; Achim Marx; Beate Kossmann; Peter Ottersbach

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An evaluation of the anti-bacterial action of ceramic powder slurries using multi-parameter flow cytometryNARA Subscribed

Biotechnology Letters · 2001 · Vol. 23 · Issue 9 · Springer

Christopher J. Hewitt; Sanjay R. Bellara; Andrea Andreani; Gerhard Nebe-von-Caron; Caroline M. McFarlane

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An application of bacterial flow cytometry: Evaluation of the toxic effects of four heavy metals on Acinetobacter sp. with potential for bioremediation of contaminated wastewatersNARA Subscribed

Biotechnology Letters · 1998 · Vol. 20 · Issue 9 · Springer

Christopher D. Boswell; Christopher J. Hewitt; Lynne E. Macaskie

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